SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yyc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1yyc PUTATIVE LATE
EMBRYOGENESIS
ABUNDANT PROTEIN
(Arabidopsis
thaliana) 		5 / 10 LEU A 141
ILE A  80
GLY A 103
VAL A  49
ILE A 143
 None
 0.97A 1sdtA-1yycA:
undetectable		 1sdtA-1yycA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1yyc PUTATIVE LATE
EMBRYOGENESIS
ABUNDANT PROTEIN
(Arabidopsis
thaliana) 		5 / 11 LEU A 141
ILE A  80
GLY A 103
VAL A  49
ILE A 143
 None
 0.99A 1sduA-1yycA:
undetectable		 1sduA-1yycA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1yyc PUTATIVE LATE
EMBRYOGENESIS
ABUNDANT PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ILE A 137
TYR A  64
VAL A  62
GLY A  61
 None
 0.77A 3em0B-1yycA:
undetectable		 3em0B-1yycA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1yyc PUTATIVE LATE
EMBRYOGENESIS
ABUNDANT PROTEIN
(Arabidopsis
thaliana) 		5 / 11 ALA A  31
VAL A 152
GLY A 153
THR A  44
PRO A  45
 None
 0.89A 3ufnA-1yycA:
undetectable		 3ufnA-1yycA:
18.54