SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1yz1 TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN
(Homo
sapiens) 		4 / 6 ASP A 154
GLY A 155
THR A 157
PRO A 158
 None
 0.71A 1n4fA-1yz1A:
undetectable		 1n4fA-1yz1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1yz1 TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN
(Homo
sapiens) 		5 / 12 TYR A  18
GLY A  33
LEU A  29
PHE A 162
HIS A  76
 None
 1.10A 3e23A-1yz1A:
undetectable		 3e23A-1yz1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1yz1 TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN
(Homo
sapiens) 		3 / 3 HIS A  77
SER A  15
GLU A  12
 None
 0.70A 3s8pA-1yz1A:
undetectable		 3s8pA-1yz1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1yz1 TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  31
LEU A  78
PHE A  14
MET A 145
LEU A 167
 None
 1.23A 4eckA-1yz1A:
undetectable		 4eckA-1yz1A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1yz1 TRANSLATIONALLY
CONTROLLED TUMOR
PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  31
GLU A  30
ILE A  72
 None
 0.66A 6f7lB-1yz1A:
undetectable		 6f7lB-1yz1A:
16.70