SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		4 / 4 LEU A  89
ARG A  98
LEU A  99
ALA A  27
 None
None
None
GDP  A 181 (-4.0A)
 1.21A 3b9mA-1yzgA:
undetectable		 3b9mA-1yzgA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		5 / 12 ILE A  67
LEU A  99
ALA A 100
LYS A 103
ILE A 122
 None
 1.03A 3dauA-1yzgA:
undetectable		 3dauA-1yzgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		4 / 8 ILE A  48
SER A  76
GLY A  49
PRO A  46
 None
 0.94A 3lslA-1yzgA:
undetectable
3lslD-1yzgA:
undetectable		 3lslA-1yzgA:
19.85
3lslD-1yzgA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		5 / 12 ILE A  67
LEU A  99
ALA A 100
LYS A 103
ILE A 122
 None
 0.94A 4psyA-1yzgA:
undetectable		 4psyA-1yzgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		5 / 9 TYR A  81
ILE A  87
LEU A  89
ARG A 108
ILE A  67
 None
 0.99A 5ifuB-1yzgA:
undetectable		 5ifuB-1yzgA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		5 / 12 VAL A  91
ILE A  88
ILE A 122
PHE A  12
ALA A 159
 None
None
None
None
GDP  A 181 (-3.3A)
 1.00A 6ajiA-1yzgA:
undetectable		 6ajiA-1yzgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1yzg ADP-RIBOSYLATION
FACTOR-LIKE 8
(Homo
sapiens) 		5 / 12 LEU A  24
GLY A  68
VAL A  22
LEU A  89
ILE A  87
 None
 1.01A 6ectA-1yzgA:
undetectable		 6ectA-1yzgA:
17.54