SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yzx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		3 / 3 GLU A 112
GLU A 115
LEU A 103
 None
 0.73A 1v8bA-1yzxA:
undetectable		 1v8bA-1yzxA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		3 / 3 GLU A 112
GLU A 115
LEU A 103
 None
 0.74A 1v8bB-1yzxA:
undetectable		 1v8bB-1yzxA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		3 / 3 LEU A 210
ASN A  34
ARG A   6
 None
 0.95A 2qhfA-1yzxA:
undetectable		 2qhfA-1yzxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		4 / 5 VAL A 106
LEU A 103
ILE A 138
ALA A 142
 None
 0.83A 3n8yB-1yzxA:
undetectable		 3n8yB-1yzxA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		5 / 12 GLY A 179
ALA A 180
PHE A  11
ARG A  40
GLU A   9
 None
 0.93A 4xt8A-1yzxA:
undetectable		 4xt8A-1yzxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		4 / 7 ILE A 132
ARG A 101
THR A 104
LEU A 103
 None
 0.91A 5zcpA-1yzxA:
undetectable
5zcpJ-1yzxA:
undetectable		 5zcpA-1yzxA:
18.87
5zcpJ-1yzxA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1yzx GLUTATHIONE
S-TRANSFERASE KAPPA
1
(Homo
sapiens) 		5 / 10 ILE A  32
ARG A   6
VAL A   8
ALA A 188
LEU A  26
 None
 0.88A 6f6nA-1yzxA:
undetectable
6f6nB-1yzxA:
undetectable		 6f6nA-1yzxA:
17.94
6f6nB-1yzxA:
18.14