SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 5 TYR A 437
GLU A 327
PHE A 206
PRO A 435
 None
 1.46A 1mclA-1z01A:
0.0
1mclB-1z01A:
0.0
1mclP-1z01A:
undetectable		 1mclA-1z01A:
15.74
1mclB-1z01A:
15.74
1mclP-1z01A:
1.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 5 VAL A 301
GLY A 300
VAL A 297
TRP A 404
 None
 1.07A 1tkqB-1z01A:
undetectable		 1tkqB-1z01A:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 8 ARG A 290
HIS A 199
ARG A 348
VAL A 312
 None
 1.35A 1u1jA-1z01A:
undetectable		 1u1jA-1z01A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 7 ARG A 203
ASN A 362
ASP A 363
GLY A 200
 None
 0.82A 2f6dA-1z01A:
undetectable		 2f6dA-1z01A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKC_A_TRPA1520_0
(FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE PRNA)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		5 / 10 ILE A 222
HIS A 221
TYR A 328
GLU A 330
ASN A 215
 None
FE  A 501 (-3.4A)
None
None
FE  A 501 ( 4.4A)
 1.49A 2jkcA-1z01A:
1.3		 2jkcA-1z01A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 CYH A 105
PHE A 110
PHE A 112
 FES  A 500 (-2.3A)
FES  A 500 (-4.1A)
None
 1.00A 3cr5X-1z01A:
undetectable		 3cr5X-1z01A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 PHE A 110
CYH A  84
HIS A  86
 FES  A 500 (-4.1A)
FES  A 500 (-2.3A)
FES  A 500 (-3.2A)
 1.20A 3u9fF-1z01A:
undetectable		 3u9fF-1z01A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 PHE A 110
CYH A  84
HIS A  86
 FES  A 500 (-4.1A)
FES  A 500 (-2.3A)
FES  A 500 (-3.2A)
 1.11A 3u9fG-1z01A:
0.9		 3u9fG-1z01A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 PHE A 110
CYH A  84
HIS A  86
 FES  A 500 (-4.1A)
FES  A 500 (-2.3A)
FES  A 500 (-3.2A)
 1.18A 3u9fL-1z01A:
undetectable		 3u9fL-1z01A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 PHE A 110
CYH A  84
HIS A  86
 FES  A 500 (-4.1A)
FES  A 500 (-2.3A)
FES  A 500 (-3.2A)
 1.20A 3u9fS-1z01A:
undetectable		 3u9fS-1z01A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 6 TYR A 376
ARG A 210
ASP A 383
TYR A  33
 None
 1.47A 3wfaA-1z01A:
0.0
3wfaB-1z01A:
0.0		 3wfaA-1z01A:
20.80
3wfaB-1z01A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 ARG A 210
GLU A 385
TYR A  33
 None
 0.93A 4r29D-1z01A:
undetectable		 4r29D-1z01A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		3 / 3 ARG A  72
ASP A  56
ARG A  71
 None
 0.65A 4wq4B-1z01A:
undetectable		 4wq4B-1z01A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 6 ASP A 391
ASP A  18
ASN A  22
GLN A  27
 None
 1.09A 5l6eA-1z01A:
undetectable		 5l6eA-1z01A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		5 / 12 VAL A  77
ILE A  63
VAL A 319
TRP A 329
VAL A 141
 None
 1.28A 6ap6A-1z01A:
undetectable		 6ap6A-1z01A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		5 / 12 VAL A  77
ILE A  63
VAL A 319
TRP A 329
VAL A 141
 None
 1.28A 6ap6B-1z01A:
undetectable		 6ap6B-1z01A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT
(Pseudomonas
putida) 		4 / 8 ILE A 392
GLN A 264
THR A 294
VAL A 304
 None
 1.15A 6fbvC-1z01A:
undetectable		 6fbvC-1z01A:
17.72