SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 9 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.97A 1c9sA-1z0fA:
undetectable
1c9sB-1z0fA:
undetectable
1c9sA-1z0fA:
16.57
1c9sB-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.97A 1c9sB-1z0fA:
undetectable
1c9sC-1z0fA:
undetectable
1c9sB-1z0fA:
16.57
1c9sC-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 1c9sG-1z0fA:
undetectable
1c9sH-1z0fA:
undetectable
1c9sG-1z0fA:
16.57
1c9sH-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 1gtfC-1z0fA:
undetectable
1gtfD-1z0fA:
undetectable
1gtfC-1z0fA:
16.57
1gtfD-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 9 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 1gtfF-1z0fA:
undetectable
1gtfG-1z0fA:
undetectable
1gtfF-1z0fA:
16.57
1gtfG-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 1gtfG-1z0fA:
undetectable
1gtfH-1z0fA:
undetectable
1gtfG-1z0fA:
16.57
1gtfH-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.98A 1gtfH-1z0fA:
undetectable
1gtfI-1z0fA:
undetectable
1gtfH-1z0fA:
16.57
1gtfI-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 GLY A  86
ALA A 109
THR A 117
ILE A 119
ARG A  82
None
0.99A 1gtfU-1z0fA:
undetectable
1gtfV-1z0fA:
undetectable
1gtfU-1z0fA:
16.57
1gtfV-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.03A 1gtnB-1z0fA:
undetectable
1gtnC-1z0fA:
undetectable
1gtnB-1z0fA:
16.57
1gtnC-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 1gtnH-1z0fA:
undetectable
1gtnI-1z0fA:
undetectable
1gtnH-1z0fA:
16.57
1gtnI-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 12 GLY A 123
ALA A 153
SER A 154
TYR A 136
ALA A 139
None
None
GDP  A 200 (-3.7A)
None
None
1.19A 1nt2A-1z0fA:
3.7
1nt2A-1z0fA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
4 / 5 MET A  89
ALA A  87
ILE A 119
ASP A 108
None
1.12A 1upfA-1z0fA:
3.7
1upfA-1z0fA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
4 / 5 MET A  89
ALA A  87
ILE A 119
ASP A 108
None
1.09A 1upfC-1z0fA:
3.7
1upfC-1z0fA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 GLY A  86
ALA A 109
THR A 117
ILE A 119
ARG A  82
None
0.99A 1utdM-1z0fA:
undetectable
1utdN-1z0fA:
undetectable
1utdM-1z0fA:
16.57
1utdN-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 9 ALA A 164
ASP A 163
GLY A 158
VAL A  90
ILE A 122
None
1.10A 2q5kA-1z0fA:
undetectable
2q5kA-1z0fA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
4 / 8 ASN A 124
ALA A 153
SER A 154
LEU A  27
GDP  A 200 (-3.3A)
None
GDP  A 200 (-3.7A)
None
1.16A 4ijiF-1z0fA:
undetectable
4ijiF-1z0fA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eeuD-1z0fA:
undetectable
5eeuE-1z0fA:
undetectable
5eeuD-1z0fA:
16.57
5eeuE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eeuH-1z0fA:
undetectable
5eeuI-1z0fA:
undetectable
5eeuH-1z0fA:
16.57
5eeuI-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 12 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.97A 5eeuI-1z0fA:
undetectable
5eeuJ-1z0fA:
undetectable
5eeuI-1z0fA:
16.57
5eeuJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 5eeuJ-1z0fA:
undetectable
5eeuK-1z0fA:
undetectable
5eeuJ-1z0fA:
16.57
5eeuK-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eevD-1z0fA:
undetectable
5eevE-1z0fA:
undetectable
5eevD-1z0fA:
16.57
5eevE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 12 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.97A 5eevI-1z0fA:
undetectable
5eevJ-1z0fA:
undetectable
5eevI-1z0fA:
16.57
5eevJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 5eevJ-1z0fA:
undetectable
5eevK-1z0fA:
undetectable
5eevJ-1z0fA:
16.57
5eevK-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eewD-1z0fA:
undetectable
5eewE-1z0fA:
undetectable
5eewD-1z0fA:
16.57
5eewE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eewH-1z0fA:
undetectable
5eewI-1z0fA:
undetectable
5eewH-1z0fA:
16.57
5eewI-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 12 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5eewI-1z0fA:
undetectable
5eewJ-1z0fA:
undetectable
5eewI-1z0fA:
16.57
5eewJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 5eewJ-1z0fA:
undetectable
5eewK-1z0fA:
undetectable
5eewJ-1z0fA:
16.57
5eewK-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eexD-1z0fA:
undetectable
5eexE-1z0fA:
undetectable
5eexD-1z0fA:
16.57
5eexE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eexH-1z0fA:
undetectable
5eexI-1z0fA:
undetectable
5eexH-1z0fA:
16.57
5eexI-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5eexI-1z0fA:
undetectable
5eexJ-1z0fA:
undetectable
5eexI-1z0fA:
16.57
5eexJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 5eexJ-1z0fA:
undetectable
5eexK-1z0fA:
undetectable
5eexJ-1z0fA:
16.57
5eexK-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eeyD-1z0fA:
undetectable
5eeyE-1z0fA:
undetectable
5eeyD-1z0fA:
16.57
5eeyE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5eeyI-1z0fA:
undetectable
5eeyJ-1z0fA:
undetectable
5eeyI-1z0fA:
16.57
5eeyJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.00A 5eeyJ-1z0fA:
undetectable
5eeyK-1z0fA:
undetectable
5eeyJ-1z0fA:
16.57
5eeyK-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5eezD-1z0fA:
undetectable
5eezE-1z0fA:
undetectable
5eezD-1z0fA:
16.57
5eezE-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5eezI-1z0fA:
undetectable
5eezJ-1z0fA:
undetectable
5eezI-1z0fA:
16.57
5eezJ-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5ef0D-1z0fA:
undetectable
5ef0E-1z0fA:
undetectable
5ef0D-1z0fA:
16.57
5ef0E-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5ef0I-1z0fA:
undetectable
5ef0J-1z0fA:
undetectable
5ef0I-1z0fA:
16.57
5ef0J-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5ef1D-1z0fA:
undetectable
5ef1E-1z0fA:
undetectable
5ef1D-1z0fA:
16.57
5ef1E-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5ef1I-1z0fA:
undetectable
5ef1J-1z0fA:
undetectable
5ef1I-1z0fA:
16.57
5ef1J-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5ef2D-1z0fA:
undetectable
5ef2E-1z0fA:
undetectable
5ef2D-1z0fA:
16.57
5ef2E-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5ef2I-1z0fA:
undetectable
5ef2J-1z0fA:
undetectable
5ef2I-1z0fA:
16.57
5ef2J-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 10 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
1.01A 5ef3D-1z0fA:
undetectable
5ef3E-1z0fA:
undetectable
5ef3D-1z0fA:
16.57
5ef3E-1z0fA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo
sapiens)
5 / 11 ARG A  82
GLY A  86
ALA A 109
THR A 117
ILE A 119
None
0.96A 5ef3I-1z0fA:
undetectable
5ef3J-1z0fA:
undetectable
5ef3I-1z0fA:
16.57
5ef3J-1z0fA:
16.57