SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 10 MET A 492
VAL A 449
ARG A 487
ILE A 522
GLY A 524
 None
 1.48A 1fohA-1z0vA:
undetectable		 1fohA-1z0vA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 10 MET A 492
VAL A 449
ARG A 487
ILE A 522
GLY A 524
 None
 1.49A 1fohC-1z0vA:
undetectable		 1fohC-1z0vA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 10 MET A 492
VAL A 449
ARG A 487
ILE A 522
GLY A 524
 None
 1.45A 1pn0A-1z0vA:
undetectable		 1pn0A-1z0vA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 10 MET A 492
VAL A 449
ARG A 487
ILE A 522
GLY A 524
 None
 1.46A 1pn0B-1z0vA:
undetectable		 1pn0B-1z0vA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 596
ILE A 481
ILE A 522
ALA A 521
 None
 0.87A 2i30A-1z0vA:
undetectable		 2i30A-1z0vA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 514
VAL A 518
ALA A 517
VAL A 595
ILE A 592
 None
 1.01A 2nnjA-1z0vA:
undetectable		 2nnjA-1z0vA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 11 SER A 513
GLY A 535
SER A 511
ASP A 508
VAL A 546
 None
 1.03A 4d9hA-1z0vA:
undetectable		 4d9hA-1z0vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 9 SER A 513
GLY A 535
SER A 511
ASP A 508
VAL A 546
 None
 1.22A 4da6A-1z0vA:
undetectable		 4da6A-1z0vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 11 SER A 513
GLY A 535
SER A 511
ASP A 508
VAL A 546
 None
 1.01A 4danA-1z0vA:
undetectable		 4danA-1z0vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 12 SER A 513
GLY A 535
SER A 511
ASP A 508
VAL A 546
 None
 1.05A 4danA-1z0vA:
undetectable
4danB-1z0vA:
undetectable		 4danA-1z0vA:
23.66
4danB-1z0vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		4 / 5 GLY A 431
VAL A 429
PRO A 444
TYR A 502
 None
 1.11A 4grkA-1z0vA:
undetectable		 4grkA-1z0vA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		4 / 6 ILE A 480
ILE A 522
PHE A 613
LEU A 596
 None
 0.65A 4m51A-1z0vA:
undetectable		 4m51A-1z0vA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 469
VAL A 543
LEU A 537
ILE A 592
 None
 0.82A 4r38A-1z0vA:
undetectable		 4r38A-1z0vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 469
VAL A 543
LEU A 537
ILE A 592
 None
 0.87A 4r38D-1z0vA:
undetectable		 4r38D-1z0vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 431
VAL A 499
ILE A 592
GLY A 535
SER A 511
 None
 1.20A 6c2mB-1z0vA:
undetectable		 6c2mB-1z0vA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 588
ILE A 566
VAL A 549
THR A 550
ILE A 553
 None
 1.08A 6hlpA-1z0vA:
undetectable		 6hlpA-1z0vA:
18.16