SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		5 / 8 TYR A  85
PHE A  65
HIS A 112
LEU A 113
VAL A 134
 None
 1.23A 1fslA-1z0xA:
undetectable		 1fslA-1z0xA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		5 / 8 TYR A  85
PHE A  81
PHE A  65
HIS A 112
LEU A 113
 None
 1.46A 1fslA-1z0xA:
undetectable		 1fslA-1z0xA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		4 / 5 THR A 206
LEU A 208
GLY A 210
TYR A  75
 None
 1.11A 1gtiF-1z0xA:
undetectable		 1gtiF-1z0xA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		4 / 7 LEU A  78
ILE A 145
MET A 144
GLN A  90
 None
 1.10A 1kglA-1z0xA:
undetectable		 1kglA-1z0xA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		5 / 12 PHE A  47
LEU A  18
LEU A  54
MET A  57
LEU A  36
 None
 1.26A 1zgyA-1z0xA:
0.0		 1zgyA-1z0xA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		5 / 8 GLU A  25
LEU A  18
LEU A  17
VAL A  32
ILE A  10
 None
 1.16A 2uxpA-1z0xA:
11.1		 2uxpA-1z0xA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		5 / 8 ALA A  58
ALA A  60
ILE A  61
PHE A  65
LEU A  88
 None
 1.45A 4v1fA-1z0xA:
undetectable
4v1fB-1z0xA:
undetectable		 4v1fA-1z0xA:
17.92
4v1fB-1z0xA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		4 / 7 ASN A  84
PRO A  68
PHE A  81
PHE A 200
 None
 1.42A 4v32A-1z0xA:
undetectable		 4v32A-1z0xA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Enterococcus
faecalis) 		4 / 7 ASN A  84
PRO A  68
PHE A  81
PHE A 200
 None
 1.44A 4v32B-1z0xA:
undetectable		 4v32B-1z0xA:
22.22