SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 8 THR X 406
CYH X 463
TYR X 439
LEU X 460
 None
HEC  X 613 (-1.9A)
HEC  X 613 (-3.5A)
None
 1.35A 1uw6A-1z1nX:
undetectable
1uw6B-1z1nX:
undetectable		 1uw6A-1z1nX:
14.64
1uw6B-1z1nX:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 5 LEU X 460
ASP X 458
PRO X 408
VAL X 407
 None
None
None
HEC  X 613 (-4.2A)
 0.99A 2aoiB-1z1nX:
undetectable		 2aoiB-1z1nX:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 5 THR X 120
GLY X 116
VAL X 114
PRO X  11
 None
 1.05A 4grkA-1z1nX:
undetectable		 4grkA-1z1nX:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		3 / 3 ARG X 196
HIS X 200
SER X 194
 HEC  X 601 ( 3.3A)
HEC  X 607 ( 3.3A)
None
 0.85A 4mjwA-1z1nX:
undetectable
4mjwB-1z1nX:
undetectable		 4mjwA-1z1nX:
21.99
4mjwB-1z1nX:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		3 / 3 SER X 194
ARG X 196
HIS X 200
 None
HEC  X 601 ( 3.3A)
HEC  X 607 ( 3.3A)
 0.84A 4mjwA-1z1nX:
undetectable
4mjwB-1z1nX:
undetectable		 4mjwA-1z1nX:
21.99
4mjwB-1z1nX:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 8 VAL X 287
GLY X 339
GLN X 344
THR X 342
 HEC  X 608 ( 4.4A)
None
HEC  X 610 (-4.6A)
None
 0.87A 5sxqA-1z1nX:
undetectable		 5sxqA-1z1nX:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 8 VAL X 287
GLY X 339
GLN X 344
THR X 342
 HEC  X 608 ( 4.4A)
None
HEC  X 610 (-4.6A)
None
 0.87A 5sxtA-1z1nX:
undetectable		 5sxtA-1z1nX:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 8 VAL X 287
GLY X 339
GLN X 344
THR X 342
 HEC  X 608 ( 4.4A)
None
HEC  X 610 (-4.6A)
None
 0.89A 5sxtB-1z1nX:
undetectable		 5sxtB-1z1nX:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		4 / 8 ALA X 230
THR X 227
THR X 120
ALA X  15
 None
 0.98A 5x2tI-1z1nX:
undetectable
5x2tJ-1z1nX:
undetectable
5x2tK-1z1nX:
undetectable
5x2tL-1z1nX:
undetectable		 5x2tI-1z1nX:
13.89
5x2tJ-1z1nX:
15.40
5x2tK-1z1nX:
13.89
5x2tL-1z1nX:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1z1n SIXTEEN HEME
CYTOCHROME
(Desulfovibrio
gigas) 		3 / 3 PHE X 487
ARG X 490
GLN X 488
 None
 1.14A 6g1pB-1z1nX:
0.0		 6g1pB-1z1nX:
20.39