SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1z1s HYPOTHETICAL PROTEIN
PA3332
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  32
LEU A  11
PHE A  34
 None
 0.67A 2pgrA-1z1sA:
undetectable		 2pgrA-1z1sA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z1s HYPOTHETICAL PROTEIN
PA3332
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 122
PRO A 121
LEU A 125
 None
 0.57A 2po5B-1z1sA:
undetectable		 2po5B-1z1sA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1z1s HYPOTHETICAL PROTEIN
PA3332
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 112
PHE A  26
ASP A 117
SER A 103
SER A  10
 None
None
PGE  A 301 (-3.1A)
PGE  A 301 ( 3.9A)
None
 1.28A 3o1xA-1z1sA:
undetectable		 3o1xA-1z1sA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1z1s HYPOTHETICAL PROTEIN
PA3332
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 112
PHE A  26
ASP A 117
SER A 103
SER A  10
 None
None
PGE  A 301 (-3.1A)
PGE  A 301 ( 3.9A)
None
 1.29A 3qgzA-1z1sA:
undetectable		 3qgzA-1z1sA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1z1s HYPOTHETICAL PROTEIN
PA3332
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  84
LEU A  62
PHE A  66
LEU A   7
TYR A 115
 None
None
PGE  A 301 (-4.8A)
None
PGE  A 301 (-4.6A)
 1.21A 5y2oA-1z1sA:
0.3		 5y2oA-1z1sA:
24.38