SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1z1z MINOR TAIL PROTEIN U
(Escherichia
virus
Lambda) 		4 / 8 ASP A 122
HIS A  63
ASP A 108
GLU A  33
 None
 1.00A 3sg9B-1z1zA:
undetectable		 3sg9B-1z1zA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1z1z MINOR TAIL PROTEIN U
(Escherichia
virus
Lambda) 		4 / 8 THR A 124
SER A 105
ASP A 122
TYR A  42
 None
 1.41A 4qb9D-1z1zA:
undetectable		 4qb9D-1z1zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1z1z MINOR TAIL PROTEIN U
(Escherichia
virus
Lambda) 		3 / 3 LEU A   6
ASP A  97
ILE A  99
 None
 0.64A 6dh0B-1z1zA:
undetectable		 6dh0B-1z1zA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1z1z MINOR TAIL PROTEIN U
(Escherichia
virus
Lambda) 		4 / 8 ASP A 122
ARG A  27
HIS A  63
GLU A  33
 None
 1.00A 6mn4C-1z1zA:
undetectable		 6mn4C-1z1zA:
19.12