SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1z24 INSECTICYANIN A FORM
(Manduca
sexta) 		4 / 7 ALA A  46
ASN A  59
TRP A 133
LEU A 135
 BLV  A 195 ( 3.9A)
BLV  A 195 (-3.7A)
BLV  A 195 (-3.7A)
None
 1.14A 2hzqA-1z24A:
19.5		 2hzqA-1z24A:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1z24 INSECTICYANIN A FORM
(Manduca
sexta) 		4 / 7 ALA A  46
TYR A  48
TRP A 133
LEU A 135
 BLV  A 195 ( 3.9A)
None
BLV  A 195 (-3.7A)
None
 0.45A 2hzqA-1z24A:
19.5		 2hzqA-1z24A:
30.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1z24 INSECTICYANIN A FORM
(Manduca
sexta) 		4 / 4 GLU A 147
GLY A 143
THR A 145
GLU A 142
 None
 0.95A 3e9xA-1z24A:
undetectable		 3e9xA-1z24A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 1z24 INSECTICYANIN A FORM
(Manduca
sexta) 		3 / 3 ARG A 188
PHE A  94
GLY A 185
 None
BLV  A 195 (-4.0A)
None
 0.73A 6fgdA-1z24A:
undetectable		 6fgdA-1z24A:
18.10