SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 1z27 OOKINETE SURFACE
PROTEIN PVS25
(Plasmodium
vivax) 		3 / 3 GLN A 109
ILE A 108
TYR A 104
 None
 0.76A 1vifA-1z27A:
undetectable		 1vifA-1z27A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 1z27 OOKINETE SURFACE
PROTEIN PVS25
(Plasmodium
vivax) 		5 / 12 ILE A 101
GLU A  99
GLU A  33
GLY A  76
VAL A  88
 None
 1.35A 3rlbB-1z27A:
undetectable		 3rlbB-1z27A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1z27 OOKINETE SURFACE
PROTEIN PVS25
(Plasmodium
vivax) 		4 / 7 ASN A  40
GLU A  41
TYR A  69
GLU A  45
 None
 1.23A 4mj8C-1z27A:
undetectable		 4mj8C-1z27A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1z27 OOKINETE SURFACE
PROTEIN PVS25
(Plasmodium
vivax) 		4 / 6 ASN A  40
GLU A  41
TYR A  69
GLU A  45
 None
 1.09A 4r87H-1z27A:
undetectable		 4r87H-1z27A:
20.39