SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		4 / 8 TYR A  74
VAL A  18
GLY A  41
GLY A  42
 None
 0.88A 1ekjE-1z3qA:
undetectable
1ekjF-1z3qA:
undetectable		 1ekjE-1z3qA:
19.49
1ekjF-1z3qA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		5 / 12 ILE A  44
THR A   2
ALA A   1
ASN A 193
SER A 113
 None
 1.35A 2gl0A-1z3qA:
undetectable
2gl0C-1z3qA:
undetectable		 2gl0A-1z3qA:
20.00
2gl0C-1z3qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		5 / 12 SER A 113
ILE A  44
THR A   2
ALA A   1
ASN A 193
 None
 1.32A 2gl0D-1z3qA:
undetectable
2gl0E-1z3qA:
undetectable		 2gl0D-1z3qA:
20.00
2gl0E-1z3qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		5 / 12 ILE A  33
ARG A  47
ALA A  16
ALA A  17
VAL A  18
 None
 0.90A 2oc8A-1z3qA:
undetectable		 2oc8A-1z3qA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		4 / 5 PRO A 178
VAL A 100
THR A  40
GLY A  41
 EDO  A 902 ( 4.7A)
EDO  A 903 (-4.3A)
None
None
 1.10A 3elzB-1z3qA:
undetectable		 3elzB-1z3qA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		5 / 12 PHE A   3
GLY A  41
GLY A  42
PRO A  19
ASP A  93
 None
 1.19A 3i5uA-1z3qA:
undetectable		 3i5uA-1z3qA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		3 / 3 ASP A 180
ARG A 169
THR A 184
 None
EDO  A 901 (-4.3A)
None
 0.83A 4i13A-1z3qA:
undetectable		 4i13A-1z3qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		3 / 3 ASP A 180
ARG A 169
THR A 184
 None
EDO  A 901 (-4.3A)
None
 0.81A 4p3rA-1z3qA:
undetectable		 4p3rA-1z3qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		3 / 3 THR A 192
ASN A  90
PHE A  89
 None
 0.83A 4pd9A-1z3qA:
undetectable		 4pd9A-1z3qA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		5 / 12 ASP A  96
SER A 110
PHE A 186
GLY A 118
ASP A 108
 EDO  A 902 ( 4.3A)
None
None
None
None
 1.28A 4pevB-1z3qA:
undetectable		 4pevB-1z3qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		3 / 3 GLY A  46
THR A  48
ASN A 104
 None
 0.56A 5odiG-1z3qA:
undetectable		 5odiG-1z3qA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW3_A_ACTA404_0
(FERREDOXIN--NADP
REDUCTASE)		 1z3q THAUMATIN-LIKE
PROTEIN
(Musa
acuminata) 		4 / 4 GLN A  24
LEU A  25
ASN A  26
GLN A  29
 None
 0.83A 5vw3A-1z3qA:
0.0		 5vw3A-1z3qA:
18.63