SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
10 / 12 ALA A 140
TYR A 142
ASP A 170
SER A 171
GLN A 172
GLU A 207
ASP A 209
GLU A 212
ARG A 240
ASP A 366
None
None
None
None
LAT  A 500 (-3.3A)
None
None
LAT  A 500 ( 4.5A)
LAT  A 500 (-3.1A)
None
0.54A 1dy4A-1z3vA:
62.2
1dy4A-1z3vA:
55.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
10 / 12 ALA A 140
TYR A 142
TYR A 168
ASP A 170
SER A 171
GLN A 172
GLU A 207
ASP A 209
GLU A 212
ASP A 366
None
None
None
None
None
LAT  A 500 (-3.3A)
None
None
LAT  A 500 ( 4.5A)
None
0.24A 1dy4A-1z3vA:
62.2
1dy4A-1z3vA:
55.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 5 HIS A 223
TRP A 364
ALA A 369
TRP A 373
LAT  A 500 ( 4.9A)
None
LAT  A 500 ( 4.3A)
LAT  A 500 (-3.7A)
0.29A 1dy4A-1z3vA:
62.2
1dy4A-1z3vA:
55.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 5 THR A   5
LEU A  73
GLY A  75
LYS A 163
TYR A 164
None
PCA  A   1 ( 4.4A)
None
None
None
1.49A 1gtiF-1z3vA:
undetectable
1gtiF-1z3vA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 11 LEU A 361
LEU A 117
LEU A 143
SER A 144
VAL A 105
None
1.17A 1ictA-1z3vA:
undetectable
1ictC-1z3vA:
undetectable
1ictA-1z3vA:
14.92
1ictC-1z3vA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 106
GLY A 167
ALA A 162
MET A 146
SER A  36
None
1.12A 1kiaA-1z3vA:
undetectable
1kiaA-1z3vA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 106
GLY A 167
ALA A 162
MET A 146
SER A  36
None
1.11A 1kiaD-1z3vA:
undetectable
1kiaD-1z3vA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 106
GLY A 167
ALA A 162
MET A 146
SER A  36
None
1.15A 1nbhA-1z3vA:
undetectable
1nbhA-1z3vA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 106
GLY A 167
ALA A 162
MET A 146
SER A  36
None
1.14A 1nbhC-1z3vA:
undetectable
1nbhC-1z3vA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A 106
GLY A 167
ALA A 162
MET A 146
SER A  36
None
1.14A 1nbhD-1z3vA:
undetectable
1nbhD-1z3vA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.30A 1rs7B-1z3vA:
undetectable
1rs7B-1z3vA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 6 PHE A 415
VAL A 413
LEU A 133
PHE A 126
None
0.92A 1wrlB-1z3vA:
undetectable
1wrlB-1z3vA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 TYR A 155
PHE A 179
ASN A 158
GLY A 151
None
PCA  A   1 ( 3.6A)
PCA  A   1 ( 3.6A)
None
1.07A 1ykiA-1z3vA:
undetectable
1ykiB-1z3vA:
undetectable
1ykiA-1z3vA:
17.91
1ykiB-1z3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 TYR A 155
PHE A 179
ASN A 158
GLY A 151
None
PCA  A   1 ( 3.6A)
PCA  A   1 ( 3.6A)
None
1.08A 1ykiA-1z3vA:
undetectable
1ykiB-1z3vA:
undetectable
1ykiA-1z3vA:
17.91
1ykiB-1z3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 TYR A 155
PHE A 179
ASN A 158
GLY A 151
None
PCA  A   1 ( 3.6A)
PCA  A   1 ( 3.6A)
None
1.02A 1ykiC-1z3vA:
undetectable
1ykiD-1z3vA:
undetectable
1ykiC-1z3vA:
17.91
1ykiD-1z3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.24A 1zzuA-1z3vA:
undetectable
1zzuA-1z3vA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 7 LEU A  14
PRO A 274
VAL A 414
MET A 130
None
1.25A 2hrcA-1z3vA:
undetectable
2hrcA-1z3vA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 GLY A 165
ARG A  39
TYR A 106
None
0.81A 2opxA-1z3vA:
undetectable
2opxA-1z3vA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 LEU A 359
LEU A  28
PHE A 124
None
0.70A 2pgrA-1z3vA:
undetectable
2pgrA-1z3vA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 5 LEU A 133
PRO A 134
LEU A 137
ILE A 363
None
0.84A 2qd4A-1z3vA:
undetectable
2qd4A-1z3vA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 ILE A 363
ASN A 214
LYS A 265
SER A 411
None
0.89A 2zw9B-1z3vA:
undetectable
2zw9B-1z3vA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 TYR A 164
THR A 166
GLY A 182
ALA A  68
None
PCA  A   1 ( 4.9A)
PCA  A   1 ( 3.3A)
PCA  A   1 ( 3.7A)
0.72A 3jusB-1z3vA:
undetectable
3jusB-1z3vA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.18A 3n66B-1z3vA:
undetectable
3n66B-1z3vA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 TYR A 155
GLY A 151
ASP A 149
None
0.64A 3ou6C-1z3vA:
undetectable
3ou6C-1z3vA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 PRO A  12
TYR A  78
ILE A  84
VAL A 105
None
0.77A 3p4wC-1z3vA:
undetectable
3p4wC-1z3vA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 GLN A 329
THR A 323
ASN A 325
None
0.89A 3v4tE-1z3vA:
undetectable
3v4tE-1z3vA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 11 GLY A 167
ALA A 162
GLY A 150
MET A 146
VAL A 358
None
1.29A 4c5lA-1z3vA:
undetectable
4c5lA-1z3vA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 10 GLY A 167
ALA A 162
GLY A 150
MET A 146
VAL A 358
None
1.27A 4c5lD-1z3vA:
undetectable
4c5lD-1z3vA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 4 LEU A 133
PRO A 134
LEU A 137
ILE A 363
None
0.90A 4f4dB-1z3vA:
undetectable
4f4dB-1z3vA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 GLN A 348
THR A 227
THR A 228
None
0.58A 4fu9A-1z3vA:
undetectable
4fu9A-1z3vA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 GLN A 348
THR A 227
THR A 228
None
0.60A 4fufA-1z3vA:
undetectable
4fufA-1z3vA:
17.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
9 / 9 ASN A 138
ALA A 140
TYR A 142
TYR A 168
ASP A 170
GLU A 207
ASP A 209
GLU A 212
TRP A 364
None
None
None
None
None
None
None
LAT  A 500 ( 4.5A)
None
0.47A 4ipmA-1z3vA:
62.5
4ipmA-1z3vA:
55.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 7 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.09A 4kcnB-1z3vA:
undetectable
4kcnB-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
5 / 12 TYR A  51
ASN A  49
ASN A  37
GLY A 102
ASN A 195
None
1.21A 4obwA-1z3vA:
undetectable
4obwA-1z3vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
3 / 3 ASN A 132
ASP A 129
ASP A 270
None
0.77A 4obwD-1z3vA:
undetectable
4obwD-1z3vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 5 TYR A 168
SER A 362
ASP A 209
ASP A 251
None
None
None
LAT  A 500 ( 3.8A)
1.23A 4qtuB-1z3vA:
undetectable
4qtuB-1z3vA:
19.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 5 GLY A   4
THR A   5
HIS A  42
GLY A  46
None
0.73A 4v20A-1z3vA:
65.8
4v20A-1z3vA:
63.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 LEU A 374
LEU A 133
GLY A 139
ALA A 140
None
0.76A 5f1aA-1z3vA:
undetectable
5f1aA-1z3vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 7 GLY A 197
GLY A 199
SER A 200
GLU A  55
None
0.59A 5izfA-1z3vA:
undetectable
5izfA-1z3vA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 4 ARG A 297
PHE A 220
ASP A 209
LEU A 133
None
1.44A 5uhdC-1z3vA:
0.4
5uhdC-1z3vA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.15A 5vunA-1z3vA:
undetectable
5vunA-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.10A 5vunB-1z3vA:
undetectable
5vunB-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.14A 5vuoB-1z3vA:
undetectable
5vuoB-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1z3v CELLULASE
(Phanerochaete
chrysosporium)
4 / 8 SER A 321
GLN A 329
PHE A 326
ASN A 320
None
1.15A 6auuB-1z3vA:
undetectable
6auuB-1z3vA:
23.32