SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 1z3x PUTATIVE
CYTIDYLYLTRANSFERASE
(Thermosynechococ
cus
elongatus) 		4 / 6 LEU A 104
GLN A  99
LEU A 101
GLU A 100
 None
 0.97A 3h5gB-1z3xA:
undetectable
3h5gC-1z3xA:
undetectable		 3h5gB-1z3xA:
11.80
3h5gC-1z3xA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 1z3x PUTATIVE
CYTIDYLYLTRANSFERASE
(Thermosynechococ
cus
elongatus) 		4 / 7 TYR A 165
THR A 215
LEU A 214
THR A 118
 None
 1.07A 5ov9A-1z3xA:
undetectable		 5ov9A-1z3xA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1z3x PUTATIVE
CYTIDYLYLTRANSFERASE
(Thermosynechococ
cus
elongatus) 		4 / 7 GLN A 168
GLY A 210
HIS A 211
SER A 159
 None
 1.07A 6hu9S-1z3xA:
undetectable
6hu9q-1z3xA:
2.4		 6hu9S-1z3xA:
17.26
6hu9q-1z3xA:
22.41