SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 VAL A 282
VAL A 280
TRP A 252
 None
 0.82A 1bdwA-1z47A:
undetectable
1bdwB-1z47A:
undetectable		 1bdwA-1z47A:
2.96
1bdwB-1z47A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 ALA A 267
VAL A 263
TRP A 350
 None
 0.85A 1grmA-1z47A:
undetectable		 1grmA-1z47A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 ALA A 267
VAL A 263
TRP A 350
 None
 0.85A 1grmB-1z47A:
undetectable		 1grmB-1z47A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 LEU A 168
VAL A  89
VAL A  72
VAL A  79
 None
 0.98A 1iwiA-1z47A:
undetectable		 1iwiA-1z47A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 4 ALA A 266
VAL A 263
ALA A 264
HIS A 344
 None
 1.20A 1q23A-1z47A:
undetectable		 1q23A-1z47A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 4 ALA A 266
VAL A 263
ALA A 264
HIS A 344
 None
 1.11A 1q23F-1z47A:
undetectable		 1q23F-1z47A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 4 ALA A 266
VAL A 263
ALA A 264
HIS A 344
 None
 1.16A 1q23K-1z47A:
undetectable		 1q23K-1z47A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 SER A 311
GLY A 310
ARG A 181
 None
 0.57A 1t9wA-1z47A:
0.0		 1t9wA-1z47A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 8 ALA A  62
LEU A  58
LEU A  46
ILE A  15
VAL A  44
 None
 1.36A 2uxpA-1z47A:
undetectable		 2uxpA-1z47A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 LEU A 168
VAL A  89
VAL A  72
VAL A  79
 None
 0.85A 2z97A-1z47A:
undetectable		 2z97A-1z47A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 GLY A 196
PRO A 164
LEU A 167
 None
 0.49A 3hcpB-1z47A:
2.0		 3hcpB-1z47A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 4 LEU A  46
ILE A  38
GLY A  45
PHE A 227
 None
 1.11A 4dc3A-1z47A:
undetectable		 4dc3A-1z47A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 LEU A 168
VAL A  89
VAL A  72
VAL A  79
 None
 0.93A 4l4bA-1z47A:
undetectable		 4l4bA-1z47A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 LEU A 291
MET A 345
VAL A 347
HIS A 300
THR A 319
 None
 1.46A 4ojbA-1z47A:
undetectable		 4ojbA-1z47A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 10 ASP A 288
VAL A 284
VAL A 282
LEU A 268
ALA A 266
 None
 1.22A 4yhaB-1z47A:
undetectable		 4yhaB-1z47A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 GLY A  11
ARG A  39
GLY A  41
GLU A  42
 None
 1.28A 4z2eB-1z47A:
undetectable
4z2eC-1z47A:
undetectable		 4z2eB-1z47A:
22.04
4z2eC-1z47A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 LEU A  47
ASP A 205
ALA A 209
VAL A 212
 None
 0.81A 4zbqA-1z47A:
1.5		 4zbqA-1z47A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 LEU A  60
PHE A  36
ILE A  61
 None
 0.73A 5dzk1-1z47A:
undetectable
5dzkF-1z47A:
undetectable
5dzkM-1z47A:
undetectable		 5dzk1-1z47A:
4.26
5dzkF-1z47A:
21.74
5dzkM-1z47A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 TYR A  24
ILE A  23
LEU A 219
GLY A  53
 None
None
None
CL  A 401 (-3.3A)
 0.90A 5kmdC-1z47A:
undetectable
5kmdD-1z47A:
undetectable		 5kmdC-1z47A:
21.56
5kmdD-1z47A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 ALA A 301
THR A 319
GLN A 292
VAL A 343
 None
 0.96A 6cduF-1z47A:
undetectable
6cduJ-1z47A:
undetectable		 6cduF-1z47A:
22.48
6cduJ-1z47A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 LEU A 168
VAL A  89
VAL A  72
VAL A  79
 None
 0.94A 6cp4A-1z47A:
undetectable		 6cp4A-1z47A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 ARG A 318
GLY A 322
GLU A 323
 None
 0.58A 6fgdA-1z47A:
1.3		 6fgdA-1z47A:
22.93