SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z4a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1z4a FERRITIN
(Thermotoga
maritima) 		5 / 7 GLU A 132
GLN A  15
PHE A  59
ILE A 103
PHE A 121
 None
 1.45A 2qmzA-1z4aA:
undetectable
2qmzB-1z4aA:
undetectable		 2qmzA-1z4aA:
20.85
2qmzB-1z4aA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1z4a FERRITIN
(Thermotoga
maritima) 		3 / 3 GLU A  51
GLU A 132
TRP A  44
 None
 1.33A 3hrdA-1z4aA:
undetectable
3hrdE-1z4aA:
undetectable
3hrdF-1z4aA:
undetectable		 3hrdA-1z4aA:
16.27
3hrdE-1z4aA:
16.27
3hrdF-1z4aA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1z4a FERRITIN
(Thermotoga
maritima) 		3 / 3 GLU A 132
GLU A  96
TRP A  44
 None
 1.28A 3hrdA-1z4aA:
undetectable
3hrdE-1z4aA:
undetectable
3hrdF-1z4aA:
undetectable		 3hrdA-1z4aA:
16.27
3hrdE-1z4aA:
16.27
3hrdF-1z4aA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 1z4a FERRITIN
(Thermotoga
maritima) 		5 / 12 LEU A 122
LEU A  12
SER A   5
LEU A 109
ILE A 106
 None
 1.13A 4x1fA-1z4aA:
undetectable		 4x1fA-1z4aA:
17.42