SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1z4r GENERAL CONTROL OF
AMINO ACID SYNTHESIS
PROTEIN 5-LIKE 2
(Homo
sapiens) 		3 / 3 PRO A 535
MET A 534
TYR A 538
 None
 1.08A 4qa0B-1z4rA:
undetectable		 4qa0B-1z4rA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1z4r GENERAL CONTROL OF
AMINO ACID SYNTHESIS
PROTEIN 5-LIKE 2
(Homo
sapiens) 		3 / 3 PRO A 535
MET A 534
TYR A 538
 None
 1.11A 4qa0A-1z4rA:
undetectable		 4qa0A-1z4rA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1z4r GENERAL CONTROL OF
AMINO ACID SYNTHESIS
PROTEIN 5-LIKE 2
(Homo
sapiens) 		4 / 6 ILE A 504
LEU A 598
HIS A 597
PHE A 573
 None
 0.95A 5vkqB-1z4rA:
undetectable
5vkqC-1z4rA:
undetectable		 5vkqB-1z4rA:
6.49
5vkqC-1z4rA:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1z4r GENERAL CONTROL OF
AMINO ACID SYNTHESIS
PROTEIN 5-LIKE 2
(Homo
sapiens) 		4 / 6 ILE A 504
LEU A 598
HIS A 597
PHE A 573
 None
 0.95A 5vkqC-1z4rA:
undetectable
5vkqD-1z4rA:
undetectable		 5vkqC-1z4rA:
6.49
5vkqD-1z4rA:
6.49