SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1z67 HYPOTHETICAL PROTEIN
S4005
(Shigella
flexneri) 		4 / 4 LEU A  82
GLY A  83
GLY A  79
THR A  88
 None
 0.86A 3si7A-1z67A:
undetectable		 3si7A-1z67A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1z67 HYPOTHETICAL PROTEIN
S4005
(Shigella
flexneri) 		3 / 3 SER A 105
GLY A 108
GLN A 107
 None
 0.55A 3v4tH-1z67A:
undetectable		 3v4tH-1z67A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1z67 HYPOTHETICAL PROTEIN
S4005
(Shigella
flexneri) 		5 / 8 LEU A  82
GLY A  83
VAL A  84
LEU A  92
GLY A  17
 None
 1.28A 4zauA-1z67A:
undetectable		 4zauA-1z67A:
18.73