SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 ASP A 573
TRP A 519
TYR A 418
ARG A 421
 None
 1.29A 1cebA-1z68A:
undetectable		 1cebA-1z68A:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 11 LEU A 632
VAL A 540
TYR A 625
GLY A 622
TRP A 653
 None
 1.24A 1fkpA-1z68A:
undetectable		 1fkpA-1z68A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 6 ASP A 702
ASN A 733
ASP A 703
TYR A 656
 None
 0.96A 1hpkA-1z68A:
undetectable		 1hpkA-1z68A:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 SER A 559
ASN A 491
LEU A 498
ILE A  47
LEU A  42
 None
 1.32A 1lhuA-1z68A:
undetectable		 1lhuA-1z68A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		3 / 3 ARG A 311
ASP A 228
ASN A 190
 None
 0.92A 1nbhA-1z68A:
undetectable		 1nbhA-1z68A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		3 / 3 ARG A 311
ASP A 228
ASN A 190
 None
 0.95A 1nbhD-1z68A:
undetectable		 1nbhD-1z68A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TRP A 653
GLY A 593
ALA A 633
GLY A 543
TYR A 660
 None
 1.01A 1nbiC-1z68A:
undetectable		 1nbiC-1z68A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TRP A 653
GLY A 593
ALA A 633
GLY A 543
TYR A 660
 None
 1.01A 1nbiD-1z68A:
undetectable		 1nbiD-1z68A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_A_ACTA601_0
(VANILLYL-ALCOHOL
OXIDASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 PHE A 579
ILE A 398
TYR A 450
ARG A 550
 None
 0.89A 1qltA-1z68A:
0.0		 1qltA-1z68A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_B_ACTB601_0
(VANILLYL-ALCOHOL
OXIDASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 PHE A 579
ILE A 398
TYR A 450
ARG A 550
 None
 0.86A 1qltB-1z68A:
0.0		 1qltB-1z68A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 LEU A 309
PHE A 350
GLY A 349
GLY A 348
SER A 294
 None
 1.03A 1v2xA-1z68A:
undetectable		 1v2xA-1z68A:
13.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.54A 1x70A-1z68A:
48.8		 1x70A-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		7 / 12 ARG A 123
GLU A 204
PHE A 351
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.46A 1x70A-1z68A:
48.8		 1x70A-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 ARG A 123
PHE A 350
TYR A 541
VAL A 650
TYR A 660
HIS A 734
 None
 1.03A 1x70A-1z68A:
48.8		 1x70A-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 624
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.56A 1x70B-1z68A:
48.8		 1x70B-1z68A:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 SER A 363
ILE A 362
ASP A 382
ASP A 360
 None
 0.84A 1yc5A-1z68A:
undetectable		 1yc5A-1z68A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 ILE A 367
ASN A 399
PHE A 401
TYR A 450
GLU A 396
 None
 1.05A 2bxfA-1z68A:
undetectable		 2bxfA-1z68A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 ILE A 367
ASN A 399
PHE A 401
TYR A 450
GLU A 396
 None
 1.10A 2bxfB-1z68A:
2.0		 2bxfB-1z68A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 8 TYR A 589
TYR A 677
ASN A 673
GLU A 662
 None
 1.13A 2fl5E-1z68A:
undetectable
2fl5F-1z68A:
undetectable		 2fl5E-1z68A:
14.78
2fl5F-1z68A:
15.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 GLU A 203
GLU A 204
TRP A 623
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
VAL A 705
HIS A 734
 None
 0.49A 2rguA-1z68A:
48.5		 2rguA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		8 / 12 GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
 None
 0.75A 2rguA-1z68A:
48.5		 2rguA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		7 / 12 PHE A 350
TRP A 623
SER A 624
TYR A 625
VAL A 650
TYR A 660
HIS A 734
 None
 0.94A 2rguA-1z68A:
48.5		 2rguA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 PHE A 350
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 660
 None
 1.14A 2rguA-1z68A:
48.5		 2rguA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TRP A 623
TYR A 628
TYR A 656
VAL A 705
HIS A 734
 None
 1.13A 2rguA-1z68A:
48.5		 2rguA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 11 GLU A 203
GLU A 204
TRP A 623
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
VAL A 705
HIS A 734
 None
 0.47A 2rguB-1z68A:
48.6		 2rguB-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		7 / 11 GLU A 203
GLU A 204
TYR A 541
TYR A 625
VAL A 650
TYR A 656
TYR A 660
 None
 0.75A 2rguB-1z68A:
48.6		 2rguB-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 11 TRP A 623
TYR A 628
TYR A 656
VAL A 705
HIS A 734
 None
 1.11A 2rguB-1z68A:
48.6		 2rguB-1z68A:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_A_CTCA1385_0
(TETX2 PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 ASP A 573
PHE A 350
GLY A 349
PRO A 544
GLY A 542
 None
 1.44A 2y6rA-1z68A:
0.0		 2y6rA-1z68A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 ASP A 573
PHE A 350
GLY A 349
PRO A 544
GLY A 542
 None
 1.43A 2y6rC-1z68A:
undetectable		 2y6rC-1z68A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 11 ILE A 713
LEU A 634
ASN A 691
LEU A 696
LEU A 632
 None
 0.97A 3a50C-1z68A:
undetectable		 3a50C-1z68A:
18.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.48A 3bjmA-1z68A:
48.7		 3bjmA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.00A 3bjmA-1z68A:
48.7		 3bjmA-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.52A 3bjmB-1z68A:
48.7		 3bjmB-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 ARG A 123
PHE A 350
TYR A 541
SER A 624
TYR A 660
 None
 1.19A 3bjmB-1z68A:
48.7		 3bjmB-1z68A:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 GLY A 699
ILE A 697
SER A 710
HIS A 698
TRP A 623
 None
 1.50A 3bwmA-1z68A:
undetectable		 3bwmA-1z68A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 GLY A 699
ILE A 697
SER A 710
HIS A 698
TRP A 623
 None
 1.49A 3bwyA-1z68A:
2.3		 3bwyA-1z68A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 PHE A 607
LEU A 511
ALA A 570
VAL A 540
VAL A 549
 None
 1.24A 3cwkA-1z68A:
undetectable		 3cwkA-1z68A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 PRO A 232
ILE A 231
PRO A 251
TYR A 252
 None
 1.34A 3d9lA-1z68A:
undetectable
3d9lY-1z68A:
undetectable		 3d9lA-1z68A:
12.08
3d9lY-1z68A:
1.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.59A 3g0bA-1z68A:
49.4		 3g0bA-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		9 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
 None
 0.68A 3g0bA-1z68A:
49.4		 3g0bA-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 SER A 624
TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.26A 3g0bA-1z68A:
49.4		 3g0bA-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.59A 3g0bB-1z68A:
48.9		 3g0bB-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		9 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
 None
 0.67A 3g0bB-1z68A:
48.9		 3g0bB-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 SER A 624
TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.29A 3g0bB-1z68A:
48.9		 3g0bB-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 624
TYR A 625
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.63A 3g0bC-1z68A:
52.2		 3g0bC-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		9 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
 None
 0.70A 3g0bC-1z68A:
52.2		 3g0bC-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.47A 3g0bC-1z68A:
52.2		 3g0bC-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 SER A 624
TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.29A 3g0bC-1z68A:
52.2		 3g0bC-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.60A 3g0bD-1z68A:
49.2		 3g0bD-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
 None
 0.75A 3g0bD-1z68A:
49.2		 3g0bD-1z68A:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		6 / 12 SER A 624
TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.29A 3g0bD-1z68A:
49.2		 3g0bD-1z68A:
52.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 9 TYR A  79
TYR A  67
ILE A  62
TYR A  87
ILE A  89
 None
 1.20A 3p4wA-1z68A:
0.0		 3p4wA-1z68A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 TYR A  67
ILE A  62
TYR A  87
ILE A  89
ILE A  76
 None
 0.90A 3p4wD-1z68A:
undetectable		 3p4wD-1z68A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 TYR A  67
ILE A  62
TYR A  87
ILE A  89
ILE A  76
 None
 0.89A 3p4wE-1z68A:
undetectable		 3p4wE-1z68A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 VAL A 647
LEU A 744
TYR A 745
LEU A 537
 None
 0.95A 3qeoB-1z68A:
2.4		 3qeoB-1z68A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 VAL A 647
LEU A 744
TYR A 745
LEU A 752
 None
 1.04A 3qeoB-1z68A:
2.4		 3qeoB-1z68A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 GLN A 483
ILE A 424
GLY A 479
ALA A 463
ALA A 453
 None
 1.03A 3sudC-1z68A:
undetectable		 3sudC-1z68A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 GLN A 483
ILE A 424
GLY A 479
ALA A 463
ALA A 453
 None
 1.02A 3sueA-1z68A:
undetectable		 3sueA-1z68A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		3 / 3 LYS A 375
ARG A 663
LEU A 585
 None
 1.07A 3v4tE-1z68A:
undetectable		 3v4tE-1z68A:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.50A 3w2tA-1z68A:
48.7		 3w2tA-1z68A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.06A 3w2tA-1z68A:
48.7		 3w2tA-1z68A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.49A 3w2tB-1z68A:
48.7		 3w2tB-1z68A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.05A 3w2tB-1z68A:
48.7		 3w2tB-1z68A:
53.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 ILE A 286
VAL A 312
LEU A 667
ASP A 290
 None
 1.16A 3wzdA-1z68A:
undetectable		 3wzdA-1z68A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		3 / 3 GLU A 340
GLY A 348
SER A 316
 None
 0.45A 4b53B-1z68A:
undetectable		 4b53B-1z68A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 8 SER A 546
GLN A 600
ILE A 516
VAL A 513
 None
 1.01A 4dx7B-1z68A:
undetectable		 4dx7B-1z68A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 8 ASN A 704
ASP A 702
VAL A 650
HIS A 698
 None
 1.23A 4f5zA-1z68A:
12.7		 4f5zA-1z68A:
17.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
VAL A 650
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 0.50A 4ffwA-1z68A:
49.1		 4ffwA-1z68A:
54.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
VAL A 650
TYR A 656
TYR A 660
VAL A 705
HIS A 734
 None
 0.58A 4ffwB-1z68A:
47.9		 4ffwB-1z68A:
54.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		7 / 12 ARG A 123
PHE A 350
TYR A 541
SER A 624
VAL A 650
TYR A 660
HIS A 734
 None
 1.11A 4ffwB-1z68A:
47.9		 4ffwB-1z68A:
54.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_B_ACTB301_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 ASN A 399
TYR A 450
PHE A 579
ARG A 550
 None
 1.47A 4g19B-1z68A:
0.0		 4g19B-1z68A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_C_ACTC301_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 ASN A 399
TYR A 450
PHE A 579
ARG A 550
 None
 1.46A 4g19C-1z68A:
0.0		 4g19C-1z68A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 ALA A 633
SER A 630
VAL A 682
ARG A 685
 None
 0.99A 4ijiH-1z68A:
undetectable		 4ijiH-1z68A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 VAL A 540
TYR A 541
GLY A 593
SER A 624
GLY A 627
 None
 1.13A 4mm8A-1z68A:
undetectable		 4mm8A-1z68A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 VAL A 540
TYR A 541
GLY A 593
SER A 624
GLY A 627
 None
 1.09A 4mmdA-1z68A:
undetectable		 4mmdA-1z68A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 VAL A 540
TYR A 541
GLY A 593
SER A 624
GLY A 627
 None
 1.15A 4mmdB-1z68A:
undetectable		 4mmdB-1z68A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 ILE A 697
VAL A 647
PHE A 641
HIS A 743
 None
 1.20A 4rzvA-1z68A:
undetectable		 4rzvA-1z68A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 7 TYR A 694
GLY A 627
SER A 630
LEU A 632
 None
 1.01A 5bphB-1z68A:
2.4		 5bphB-1z68A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 8 ILE A 339
ILE A 390
ILE A 429
ILE A 377
PHE A 368
 None
 1.48A 5hi2A-1z68A:
undetectable		 5hi2A-1z68A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		3 / 3 ASP A 478
ASN A  80
GLN A  65
 None
 0.71A 5k7uA-1z68A:
undetectable		 5k7uA-1z68A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 TYR A  79
TYR A  67
ILE A  62
TYR A  87
ILE A  89
 None
 1.21A 5mzrA-1z68A:
undetectable		 5mzrA-1z68A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 10 TYR A  79
TYR A  67
ILE A  62
TYR A  87
ILE A  89
 None
 1.21A 5mzrC-1z68A:
undetectable		 5mzrC-1z68A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 TYR A 745
MET A 748
THR A 749
LEU A 752
 None
 1.19A 5w97J-1z68A:
undetectable		 5w97J-1z68A:
7.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 541
SER A 624
TYR A 625
VAL A 650
TYR A 656
TYR A 660
ASN A 704
VAL A 705
HIS A 734
 None
 0.50A 6b1eB-1z68A:
48.9		 6b1eB-1z68A:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 TYR A 628
TYR A 656
ASN A 704
VAL A 705
HIS A 734
 None
 1.04A 6b1eB-1z68A:
48.9		 6b1eB-1z68A:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		5 / 12 GLN A 483
ILE A 424
GLY A 479
ALA A 463
ALA A 453
 None
 0.98A 6c2mD-1z68A:
undetectable		 6c2mD-1z68A:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 TYR A 745
MET A 748
THR A 749
LEU A 752
 None
 1.19A 6nknJ-1z68A:
undetectable		 6nknJ-1z68A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens) 		4 / 5 TYR A 745
MET A 748
THR A 749
LEU A 752
 None
 1.08A 6nknW-1z68A:
undetectable		 6nknW-1z68A:
7.25