SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK2_A_T44A3002_1 (SERUM ALBUMIN)	1z6g	GUANYLATE KINASE (Plasmodium falciparum)	4 / 8	LEU A 168 LEU A 186 TYR A 190 LEU A 99	None	1.17A	1hk2A-1z6gA: undetectable	1hk2A-1z6gA: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SKX_A_RFPA1_1 (ORPHAN NUCLEAR RECEPTOR PXR)	1z6g	GUANYLATE KINASE (Plasmodium falciparum)	5 / 12	VAL A 107 LEU A 99 SER A 37 ILE A 21 PHE A 34	None	1.33A	1skxA-1z6gA: 0.0	1skxA-1z6gA: 23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	1z6g	GUANYLATE KINASE (Plasmodium falciparum)	4 / 8	GLY A 11 VAL A 15 LEU A 132 PRO A 126	None SO4 A 400 (-4.1A) None None	1.03A	3bgdB-1z6gA: undetectable	3bgdB-1z6gA: 24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_B_CVIB301_0 (PUTATIVE REGULATORY PROTEIN)	1z6g	GUANYLATE KINASE (Plasmodium falciparum)	5 / 12	ILE A 191 TYR A 190 PHE A 32 LEU A 7 LEU A 25	None	1.35A	3vw1B-1z6gA: undetectable	3vw1B-1z6gA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZ8_A_GCSA208_1 (GLUCANASE/CHITOSANAS E)	1z6g	GUANYLATE KINASE (Plasmodium falciparum)	4 / 7	ARG A 44 TYR A 81 GLU A 47 ASP A 52	None	1.08A	4zz8A-1z6gA: undetectable	4zz8A-1z6gA: 19.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK2_A_T44A3002_1","SERUM ALBUMIN","1z6g","GUANYLATE KINASE","Plasmodium falciparum",4,"LEU A 168;LEU A 186;TYR A 190;LEU A  99","None","1.17A","1hk2A-1z6gA:undetectable","1hk2A-1z6gA:17.09"],["1SKX_A_RFPA1_1","ORPHAN NUCLEAR RECEPTOR PXR","1z6g","GUANYLATE KINASE","Plasmodium falciparum",5,"VAL A 107;LEU A  99;SER A  37;ILE A  21;PHE A  34","None","1.33A","1skxA-1z6gA:0.0","1skxA-1z6gA:23.77"],["3BGD_B_PM6B301_1","THIOPURINE S-METHYLTRANSFERASE","1z6g","GUANYLATE KINASE","Plasmodium falciparum",4,"GLY A  11;VAL A  15;LEU A 132;PRO A 126","None;SO4 A 400 (-4.1A);None;None","1.03A","3bgdB-1z6gA:undetectable","3bgdB-1z6gA:24.82"],["3VW1_B_CVIB301_0","PUTATIVE REGULATORY PROTEIN","1z6g","GUANYLATE KINASE","Plasmodium falciparum",5,"ILE A 191;TYR A 190;PHE A  32;LEU A   7;LEU A  25","None","1.35A","3vw1B-1z6gA:undetectable","3vw1B-1z6gA:21.07"],["4ZZ8_A_GCSA208_1","GLUCANASE\/CHITOSANASE","1z6g","GUANYLATE KINASE","Plasmodium falciparum",4,"ARG A  44;TYR A  81;GLU A  47;ASP A  52","None","1.08A","4zz8A-1z6gA:undetectable","4zz8A-1z6gA:19.16"]]