SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 100
LEU A 104
VAL A  60
ARG A  57
TYR A   4
 None
 1.44A 1y4lB-1z6nA:
undetectable		 1y4lB-1z6nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 101
GLU A 107
GLN A 102
 None
 0.91A 2p16A-1z6nA:
undetectable		 2p16A-1z6nA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  49
LEU A  45
ILE A  52
ARG A  51
 None
 0.90A 2rlfB-1z6nA:
undetectable
2rlfC-1z6nA:
undetectable		 2rlfB-1z6nA:
16.15
2rlfC-1z6nA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  76
ALA A  79
LEU A  45
LEU A 151
LEU A 159
 None
 1.04A 3hm1A-1z6nA:
undetectable		 3hm1A-1z6nA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.43A 3k39B-1z6nA:
undetectable		 3k39B-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.44A 3k39C-1z6nA:
undetectable		 3k39C-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.44A 3k39I-1z6nA:
0.2		 3k39I-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.45A 3k39J-1z6nA:
0.2		 3k39J-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.44A 3k39K-1z6nA:
undetectable		 3k39K-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 103
LEU A  59
ASP A  99
ARG A  95
GLU A   6
 None
 1.44A 3k39L-1z6nA:
undetectable		 3k39L-1z6nA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  31
PRO A  67
PHE A  32
 None
 0.82A 3thrC-1z6nA:
undetectable		 3thrC-1z6nA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1z6n HYPOTHETICAL PROTEIN
PA1234
(Pseudomonas
aeruginosa) 		4 / 5 ALA A  74
ARG A  81
ALA A  30
GLU A  37
 None
 1.28A 5a06C-1z6nA:
undetectable
5a06D-1z6nA:
undetectable		 5a06C-1z6nA:
22.06
5a06D-1z6nA:
22.06