SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 11 SER A  16
SER A  18
LEU A  19
ALA A  20
LEU A  21
 None
 1.42A 1hwkB-1z6oA:
undetectable		 1hwkB-1z6oA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 11 SER A  16
SER A  18
LEU A  19
ALA A  20
LEU A  21
 None
 1.42A 1hwkA-1z6oA:
undetectable		 1hwkA-1z6oA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 11 SER A  16
SER A  18
LEU A  19
ALA A  20
LEU A  21
 None
 1.43A 1hwkC-1z6oA:
undetectable		 1hwkC-1z6oA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 7 GLU M  66
GLU M 152
GLU M 116
GLU M  67
 None
None
None
FE  M 300 (-2.5A)
 1.20A 1knyA-1z6oM:
2.3
1knyB-1z6oM:
3.4		 1knyA-1z6oM:
21.53
1knyB-1z6oM:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		5 / 12 PHE M 149
LEU M 141
MET M  25
ILE M  29
LEU M  78
 None
 1.30A 1lhuA-1z6oM:
undetectable		 1lhuA-1z6oM:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 LEU A 197
ASN M   4
LEU A 201
PHE A  72
ALA A 125
 None
 1.22A 1n5xA-1z6oA:
2.3		 1n5xA-1z6oA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 LEU A 197
ASN M   4
LEU A 201
PHE A  72
ALA A 125
 None
 1.22A 1n5xB-1z6oA:
undetectable		 1n5xB-1z6oA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		3 / 3 THR A 132
GLU A  50
ASP A 104
 None
 0.83A 1nt2A-1z6oA:
undetectable		 1nt2A-1z6oA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 6 GLU M  66
ALA M  35
LEU M  37
VAL M 119
 None
 1.08A 1sn5A-1z6oM:
undetectable		 1sn5A-1z6oM:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  59
ALA A  60
LEU M  79
VAL M  33
LEU M  91
 None
 0.92A 1xlsA-1z6oA:
undetectable		 1xlsA-1z6oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  59
ALA A  60
LEU M  79
VAL M  33
LEU M  91
 None
 0.92A 1xlsB-1z6oA:
undetectable		 1xlsB-1z6oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  59
ALA A  60
LEU M  79
VAL M  33
LEU M  91
 None
 0.92A 1xlsC-1z6oA:
undetectable		 1xlsC-1z6oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  59
ALA A  60
LEU M  79
VAL M  33
LEU M  91
 None
 0.92A 1xlsD-1z6oA:
undetectable		 1xlsD-1z6oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN
(Trichoplusia
ni;
Trichoplusia
ni) 		4 / 7 VAL M  88
LEU M  79
PHE A  62
THR A  67
 None
 1.04A 2f78A-1z6oM:
undetectable		 2f78A-1z6oM:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN
(Trichoplusia
ni;
Trichoplusia
ni) 		4 / 7 VAL M  88
LEU M  79
PHE A  62
THR A  67
 None
 1.08A 2f78B-1z6oM:
undetectable		 2f78B-1z6oM:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN
(Trichoplusia
ni;
Trichoplusia
ni) 		3 / 3 ARG M  68
SER M  65
TYR A  53
 None
 0.93A 2q2hA-1z6oM:
undetectable
2q2hB-1z6oM:
undetectable		 2q2hA-1z6oM:
22.28
2q2hB-1z6oM:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 GLN M 157
TYR M 154
ARG M 124
GLN M  28
 None
 1.38A 2vxaA-1z6oM:
undetectable
2vxaB-1z6oM:
undetectable
2vxaK-1z6oM:
undetectable		 2vxaA-1z6oM:
18.67
2vxaB-1z6oM:
18.67
2vxaK-1z6oM:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 GLN M  28
TYR M 154
ARG M 124
GLN M 157
 None
 1.38A 2vxaF-1z6oM:
undetectable
2vxaG-1z6oM:
undetectable
2vxaI-1z6oM:
undetectable		 2vxaF-1z6oM:
18.67
2vxaG-1z6oM:
18.67
2vxaI-1z6oM:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 GLN M 157
TYR M 154
ARG M 124
GLN M  28
 None
 1.35A 2vxaH-1z6oM:
undetectable
2vxaI-1z6oM:
undetectable
2vxaJ-1z6oM:
undetectable		 2vxaH-1z6oM:
18.67
2vxaI-1z6oM:
18.67
2vxaJ-1z6oM:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 GLN M  28
GLN M 157
TYR M 154
ARG M 124
 None
 1.36A 2vxaH-1z6oM:
undetectable
2vxaJ-1z6oM:
undetectable
2vxaK-1z6oM:
undetectable		 2vxaH-1z6oM:
18.67
2vxaJ-1z6oM:
18.67
2vxaK-1z6oM:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 GLN M  28
GLN M 157
TYR M 154
ARG M 124
 None
 1.36A 2vxaA-1z6oM:
undetectable
2vxaK-1z6oM:
undetectable
2vxaL-1z6oM:
undetectable		 2vxaA-1z6oM:
18.67
2vxaK-1z6oM:
18.67
2vxaL-1z6oM:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 8 LEU M 113
LEU M 160
LYS M 163
ALA M 164
 None
 0.75A 2wekA-1z6oM:
undetectable		 2wekA-1z6oM:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN
(Trichoplusia
ni;
Trichoplusia
ni) 		4 / 5 PRO M  96
THR A  95
VAL A  94
LYS M  48
 None
 0.97A 3elzA-1z6oM:
undetectable		 3elzA-1z6oM:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6o FERRITIN HEAVY CHAIN
FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  59
ALA A  60
LEU M  79
VAL M  33
LEU M  91
 None
 0.92A 3h0aA-1z6oA:
undetectable		 3h0aA-1z6oA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9W_A_VGHA1158_1
(7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		5 / 12 PHE M  46
VAL M  51
TRP M 102
PHE M  60
GLN M  38
 None
 1.03A 4c9wA-1z6oM:
undetectable		 4c9wA-1z6oM:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 7 MET M 171
VAL M 106
PHE M  56
GLU M 175
 None
 1.49A 4jseA-1z6oM:
undetectable
4jseB-1z6oM:
1.7		 4jseA-1z6oM:
16.67
4jseB-1z6oM:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		3 / 3 GLU A 158
ARG A  97
HIS A  93
 None
 0.85A 4kf9A-1z6oA:
undetectable		 4kf9A-1z6oA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		3 / 3 GLN M  38
HIS M 111
ARG M  99
 None
 1.28A 4qyqA-1z6oM:
0.0		 4qyqA-1z6oM:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		3 / 3 GLN M  38
HIS M 111
ARG M  99
 None
 1.25A 4qyqB-1z6oM:
undetectable		 4qyqB-1z6oM:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 1z6o FERRITIN LIGHT CHAIN
(Trichoplusia
ni) 		5 / 12 ALA A  70
GLY A  71
ASN A 120
GLU A 124
LEU A 126
 None
 1.18A 5nwuA-1z6oA:
undetectable		 5nwuA-1z6oA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN
(Trichoplusia
ni;
Trichoplusia
ni) 		3 / 3 SER A  80
SER A  52
ALA M  71
 None
 0.72A 6dwnC-1z6oA:
undetectable		 6dwnC-1z6oA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1z6o FERRITIN HEAVY CHAIN
(Trichoplusia
ni) 		4 / 6 MET M 171
ALA M 108
LEU M 109
ALA M 164
 None
 1.19A 6fosB-1z6oM:
3.2		 6fosB-1z6oM:
17.02