SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.29A 1c9sA-1z6rA:
undetectable
1c9sK-1z6rA:
undetectable		 1c9sA-1z6rA:
11.00
1c9sK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.28A 1c9sA-1z6rA:
undetectable
1c9sB-1z6rA:
undetectable		 1c9sA-1z6rA:
11.00
1c9sB-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 1c9sE-1z6rA:
undetectable
1c9sF-1z6rA:
undetectable		 1c9sE-1z6rA:
11.00
1c9sF-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.28A 1c9sG-1z6rA:
undetectable
1c9sH-1z6rA:
undetectable		 1c9sG-1z6rA:
11.00
1c9sH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 1c9sH-1z6rA:
undetectable
1c9sI-1z6rA:
undetectable		 1c9sH-1z6rA:
11.00
1c9sI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.26A 1c9sJ-1z6rA:
undetectable
1c9sK-1z6rA:
undetectable		 1c9sJ-1z6rA:
11.00
1c9sK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 1c9sM-1z6rA:
undetectable
1c9sN-1z6rA:
undetectable		 1c9sM-1z6rA:
11.00
1c9sN-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 1c9sS-1z6rA:
undetectable
1c9sT-1z6rA:
undetectable		 1c9sS-1z6rA:
11.00
1c9sT-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 CYH A 301
ALA A 303
ALA A 304
LEU A 290
VAL A 271
 None
 0.89A 1fbyA-1z6rA:
undetectable		 1fbyA-1z6rA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 CYH A 301
ALA A 303
ALA A 304
LEU A 290
VAL A 271
 None
 0.91A 1fbyB-1z6rA:
undetectable		 1fbyB-1z6rA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.28A 1gtfA-1z6rA:
undetectable
1gtfK-1z6rA:
undetectable		 1gtfA-1z6rA:
11.00
1gtfK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 1gtfE-1z6rA:
undetectable
1gtfF-1z6rA:
undetectable		 1gtfE-1z6rA:
11.00
1gtfF-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 1gtfF-1z6rA:
undetectable
1gtfG-1z6rA:
undetectable		 1gtfF-1z6rA:
11.00
1gtfG-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.28A 1gtfH-1z6rA:
undetectable
1gtfI-1z6rA:
undetectable		 1gtfH-1z6rA:
11.00
1gtfI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 1gtfI-1z6rA:
undetectable
1gtfJ-1z6rA:
undetectable		 1gtfI-1z6rA:
11.00
1gtfJ-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 6 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.35A 1gtnD-1z6rA:
undetectable
1gtnE-1z6rA:
undetectable		 1gtnD-1z6rA:
11.00
1gtnE-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.26A 1gtnG-1z6rA:
undetectable
1gtnH-1z6rA:
undetectable		 1gtnG-1z6rA:
11.00
1gtnH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 11 LEU A  59
ALA A 202
ALA A 387
TYR A 395
LEU A 399
 None
 1.30A 1hbpA-1z6rA:
undetectable		 1hbpA-1z6rA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 HIS A 291
LEU A 282
ALA A 278
LEU A 310
LEU A 300
 None
 1.39A 1hwiA-1z6rA:
undetectable		 1hwiA-1z6rA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 11 LEU A  59
ALA A 202
ALA A 387
TYR A 395
LEU A 399
 None
 1.19A 1iiuA-1z6rA:
undetectable		 1iiuA-1z6rA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.31A 1utdA-1z6rA:
undetectable
1utdB-1z6rA:
undetectable		 1utdA-1z6rA:
11.00
1utdB-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 8 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.29A 1utdB-1z6rA:
undetectable
1utdC-1z6rA:
undetectable		 1utdB-1z6rA:
11.00
1utdC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 1utdC-1z6rA:
undetectable
1utdD-1z6rA:
undetectable		 1utdC-1z6rA:
11.00
1utdD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.30A 1utdG-1z6rA:
undetectable
1utdH-1z6rA:
undetectable		 1utdG-1z6rA:
11.00
1utdH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 8 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.26A 1utdJ-1z6rA:
undetectable
1utdK-1z6rA:
undetectable		 1utdJ-1z6rA:
11.00
1utdK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 ASP A 195
ARG A  91
ASP A 221
 None
 0.89A 1vptA-1z6rA:
undetectable		 1vptA-1z6rA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		6 / 12 GLU A 266
GLY A 225
GLY A 246
ILE A 325
ASP A 195
ILE A 196
 None
 1.44A 1x1aA-1z6rA:
2.3		 1x1aA-1z6rA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		6 / 12 GLU A 266
HIS A 247
GLY A 225
ILE A 325
ASP A 195
ILE A 196
 None
ZN  A 501 (-3.0A)
None
None
None
None
 1.10A 1x1aA-1z6rA:
2.3		 1x1aA-1z6rA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 CYH A 301
ALA A 303
ALA A 304
LEU A 290
VAL A 271
 None
 0.88A 1xiuA-1z6rA:
undetectable		 1xiuA-1z6rA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 5 ILE A 163
LEU A 125
ALA A 181
GLU A 180
 None
 1.26A 1xvaA-1z6rA:
undetectable
1xvaB-1z6rA:
undetectable		 1xvaA-1z6rA:
22.66
1xvaB-1z6rA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 THR A 248
CYH A 264
ILE A 268
ILE A 245
VAL A 250
 None
ZN  A 501 (-2.2A)
None
None
None
 1.09A 1z9hD-1z6rA:
undetectable		 1z9hD-1z6rA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 SER A 270
ASP A 272
SER A 273
LYS A 255
 None
 1.12A 2cmlD-1z6rA:
undetectable		 2cmlD-1z6rA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 CYH A 259
CYH A 264
HIS A 247
 ZN  A 501 (-2.2A)
ZN  A 501 (-2.2A)
ZN  A 501 (-3.0A)
 0.79A 2iwkA-1z6rA:
undetectable		 2iwkA-1z6rA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 CYH A 259
CYH A 264
HIS A 247
 ZN  A 501 (-2.2A)
ZN  A 501 (-2.2A)
ZN  A 501 (-3.0A)
 0.79A 2iwkB-1z6rA:
undetectable		 2iwkB-1z6rA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 HIS A 185
ILE A 149
LEU A 178
 None
 0.77A 2kceA-1z6rA:
undetectable		 2kceA-1z6rA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 ILE A 315
ILE A 274
LEU A 344
VAL A 224
ILE A 355
 None
 1.23A 2nnhB-1z6rA:
undetectable		 2nnhB-1z6rA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 SER A 379
ASP A 195
ASP A 221
 None
 0.75A 2plwA-1z6rA:
undetectable		 2plwA-1z6rA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 5 LEU A 178
PRO A 177
LEU A 125
ILE A 128
ARG A 127
 None
 1.36A 2qd4A-1z6rA:
2.8		 2qd4A-1z6rA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 VAL A 318
GLY A 319
GLY A 323
ILE A 245
ALA A 269
 None
 0.93A 2z0yA-1z6rA:
2.6		 2z0yA-1z6rA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 VAL A 318
GLY A 319
GLY A 323
ILE A 245
ALA A 269
 None
 0.84A 2z0yB-1z6rA:
2.4		 2z0yB-1z6rA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 SER A 288
GLY A 317
ILE A 274
ALA A 269
 None
 0.94A 3aodA-1z6rA:
undetectable		 3aodA-1z6rA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 205
LEU A 104
ASP A  26
SER A 148
ALA A 388
 None
 1.04A 3dfrA-1z6rA:
undetectable		 3dfrA-1z6rA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 CYH A 259
CYH A 264
HIS A 247
 ZN  A 501 (-2.2A)
ZN  A 501 (-2.2A)
ZN  A 501 (-3.0A)
 0.73A 3dtuB-1z6rA:
undetectable		 3dtuB-1z6rA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 CYH A 259
CYH A 264
HIS A 247
 ZN  A 501 (-2.2A)
ZN  A 501 (-2.2A)
ZN  A 501 (-3.0A)
 0.70A 3dtuD-1z6rA:
undetectable		 3dtuD-1z6rA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6r MLC PROTEIN
(Escherichia
coli) 		6 / 12 VAL A 297
CYH A 301
ALA A 303
ALA A 304
LEU A 290
VAL A 271
 None
 0.89A 3fc6C-1z6rA:
undetectable		 3fc6C-1z6rA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 388
ALA A 387
LEU A 205
ALA A 202
VAL A  80
 None
 0.98A 3h0aA-1z6rA:
undetectable		 3h0aA-1z6rA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 178
PRO A 177
LEU A 125
ARG A 127
 None
 1.43A 3hcoA-1z6rA:
undetectable		 3hcoA-1z6rA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 11 ILE A 355
ILE A 245
VAL A 218
VAL A 224
GLY A 246
 None
 0.97A 3kw4A-1z6rA:
undetectable		 3kw4A-1z6rA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 ILE A 314
ALA A 304
SER A 342
ILE A 220
ILE A 274
 None
 1.11A 3qgtA-1z6rA:
undetectable		 3qgtA-1z6rA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 ALA A 237
GLY A 238
GLU A 160
THR A 159
 None
 0.92A 3rglA-1z6rA:
undetectable		 3rglA-1z6rA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 SER A  89
ASP A 195
ASP A 221
 None
 0.59A 3uj7A-1z6rA:
undetectable		 3uj7A-1z6rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 5 SER A 273
ASP A 221
ASP A 195
ILE A 196
 None
 1.25A 3uj7B-1z6rA:
undetectable		 3uj7B-1z6rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 151
GLY A 155
VAL A 164
LEU A 124
ASP A 195
 None
 1.00A 3vasB-1z6rA:
undetectable		 3vasB-1z6rA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 4 PRO A 177
LEU A 125
ILE A 128
ARG A 127
 None
 1.47A 4f4dA-1z6rA:
undetectable		 4f4dA-1z6rA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 ASP A 195
ARG A  91
ASP A 221
 None
 0.87A 4fp9D-1z6rA:
undetectable		 4fp9D-1z6rA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 ASP A 195
ARG A  91
ASP A 221
 None
 0.84A 4fzvA-1z6rA:
undetectable		 4fzvA-1z6rA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 355
VAL A 322
LEU A 265
LEU A 326
LEU A 351
 None
 0.91A 4m11B-1z6rA:
undetectable		 4m11B-1z6rA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 LEU A  99
LEU A  88
LEU A 146
ILE A  97
HIS A 185
 None
 1.36A 4mk4A-1z6rA:
3.1		 4mk4A-1z6rA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 SER A  89
ASP A 195
ASP A 221
 None
 0.63A 4mwzA-1z6rA:
undetectable		 4mwzA-1z6rA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 344
SER A 345
ILE A 340
VAL A 373
 None
 1.22A 4tvtA-1z6rA:
undetectable		 4tvtA-1z6rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 326
MET A 329
VAL A 330
ASN A 334
 None
 1.31A 5b8iB-1z6rA:
0.0		 5b8iB-1z6rA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eeuB-1z6rA:
undetectable
5eeuC-1z6rA:
undetectable		 5eeuB-1z6rA:
11.00
5eeuC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eeuE-1z6rA:
undetectable
5eeuF-1z6rA:
undetectable		 5eeuE-1z6rA:
11.00
5eeuF-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eeuG-1z6rA:
undetectable
5eeuH-1z6rA:
undetectable		 5eeuG-1z6rA:
11.00
5eeuH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.28A 5eeuH-1z6rA:
undetectable
5eeuI-1z6rA:
undetectable		 5eeuH-1z6rA:
11.00
5eeuI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eeuJ-1z6rA:
undetectable
5eeuK-1z6rA:
undetectable		 5eeuJ-1z6rA:
11.00
5eeuK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eeuA-1z6rA:
undetectable
5eeuK-1z6rA:
undetectable		 5eeuA-1z6rA:
11.00
5eeuK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eevB-1z6rA:
undetectable
5eevC-1z6rA:
undetectable		 5eevB-1z6rA:
11.00
5eevC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eevC-1z6rA:
undetectable
5eevD-1z6rA:
undetectable		 5eevC-1z6rA:
11.00
5eevD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eevG-1z6rA:
undetectable
5eevH-1z6rA:
undetectable		 5eevG-1z6rA:
11.00
5eevH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eevH-1z6rA:
undetectable
5eevI-1z6rA:
undetectable		 5eevH-1z6rA:
11.00
5eevI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eevJ-1z6rA:
undetectable
5eevK-1z6rA:
undetectable		 5eevJ-1z6rA:
11.00
5eevK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eevA-1z6rA:
undetectable
5eevK-1z6rA:
undetectable		 5eevA-1z6rA:
11.00
5eevK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eewB-1z6rA:
undetectable
5eewC-1z6rA:
undetectable		 5eewB-1z6rA:
11.00
5eewC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eewC-1z6rA:
undetectable
5eewD-1z6rA:
undetectable		 5eewC-1z6rA:
11.00
5eewD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eewG-1z6rA:
undetectable
5eewH-1z6rA:
undetectable		 5eewG-1z6rA:
11.00
5eewH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eewH-1z6rA:
undetectable
5eewI-1z6rA:
undetectable		 5eewH-1z6rA:
11.00
5eewI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eewJ-1z6rA:
undetectable
5eewK-1z6rA:
undetectable		 5eewJ-1z6rA:
11.00
5eewK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eewA-1z6rA:
undetectable
5eewK-1z6rA:
undetectable		 5eewA-1z6rA:
11.00
5eewK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eexB-1z6rA:
undetectable
5eexC-1z6rA:
undetectable		 5eexB-1z6rA:
11.00
5eexC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eexC-1z6rA:
undetectable
5eexD-1z6rA:
undetectable		 5eexC-1z6rA:
11.00
5eexD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eexG-1z6rA:
undetectable
5eexH-1z6rA:
undetectable		 5eexG-1z6rA:
11.00
5eexH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eexH-1z6rA:
undetectable
5eexI-1z6rA:
undetectable		 5eexH-1z6rA:
11.00
5eexI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eexJ-1z6rA:
undetectable
5eexK-1z6rA:
undetectable		 5eexJ-1z6rA:
11.00
5eexK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eexA-1z6rA:
undetectable
5eexK-1z6rA:
undetectable		 5eexA-1z6rA:
11.00
5eexK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eeyB-1z6rA:
undetectable
5eeyC-1z6rA:
undetectable		 5eeyB-1z6rA:
11.00
5eeyC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eeyC-1z6rA:
undetectable
5eeyD-1z6rA:
undetectable		 5eeyC-1z6rA:
11.00
5eeyD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eeyG-1z6rA:
undetectable
5eeyH-1z6rA:
undetectable		 5eeyG-1z6rA:
11.00
5eeyH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5eeyH-1z6rA:
undetectable
5eeyI-1z6rA:
undetectable		 5eeyH-1z6rA:
11.00
5eeyI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eeyJ-1z6rA:
undetectable
5eeyK-1z6rA:
undetectable		 5eeyJ-1z6rA:
11.00
5eeyK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eeyA-1z6rA:
undetectable
5eeyK-1z6rA:
undetectable		 5eeyA-1z6rA:
11.00
5eeyK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.26A 5eezB-1z6rA:
undetectable
5eezC-1z6rA:
undetectable		 5eezB-1z6rA:
11.00
5eezC-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eezC-1z6rA:
undetectable
5eezD-1z6rA:
undetectable		 5eezC-1z6rA:
11.00
5eezD-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5eezG-1z6rA:
undetectable
5eezH-1z6rA:
undetectable		 5eezG-1z6rA:
11.00
5eezH-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.28A 5eezH-1z6rA:
undetectable
5eezI-1z6rA:
undetectable		 5eezH-1z6rA:
11.00
5eezI-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5eezJ-1z6rA:
undetectable
5eezK-1z6rA:
undetectable		 5eezJ-1z6rA:
11.00
5eezK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5eezA-1z6rA:
undetectable
5eezK-1z6rA:
undetectable		 5eezA-1z6rA:
11.00
5eezK-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef0B-1z6rA:
undetectable
5ef0C-1z6rA:
undetectable		 5ef0B-1z6rA:
11.00
5ef0C-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef0C-1z6rA:
undetectable
5ef0D-1z6rA:
undetectable		 5ef0C-1z6rA:
11.00
5ef0D-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef0G-1z6rA:
undetectable
5ef0H-1z6rA:
undetectable		 5ef0G-1z6rA:
11.00
5ef0H-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef0H-1z6rA:
undetectable
5ef0I-1z6rA:
undetectable		 5ef0H-1z6rA:
11.00
5ef0I-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5ef0J-1z6rA:
undetectable
5ef0K-1z6rA:
undetectable		 5ef0J-1z6rA:
11.00
5ef0K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5ef0A-1z6rA:
undetectable
5ef0K-1z6rA:
undetectable		 5ef0A-1z6rA:
11.00
5ef0K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef1B-1z6rA:
undetectable
5ef1C-1z6rA:
undetectable		 5ef1B-1z6rA:
11.00
5ef1C-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef1C-1z6rA:
undetectable
5ef1D-1z6rA:
undetectable		 5ef1C-1z6rA:
11.00
5ef1D-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef1G-1z6rA:
undetectable
5ef1H-1z6rA:
undetectable		 5ef1G-1z6rA:
11.00
5ef1H-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef1H-1z6rA:
undetectable
5ef1I-1z6rA:
undetectable		 5ef1H-1z6rA:
11.00
5ef1I-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5ef1J-1z6rA:
undetectable
5ef1K-1z6rA:
undetectable		 5ef1J-1z6rA:
11.00
5ef1K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5ef1A-1z6rA:
undetectable
5ef1K-1z6rA:
undetectable		 5ef1A-1z6rA:
11.00
5ef1K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.26A 5ef2B-1z6rA:
undetectable
5ef2C-1z6rA:
undetectable		 5ef2B-1z6rA:
11.00
5ef2C-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef2C-1z6rA:
undetectable
5ef2D-1z6rA:
undetectable		 5ef2C-1z6rA:
11.00
5ef2D-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef2G-1z6rA:
undetectable
5ef2H-1z6rA:
undetectable		 5ef2G-1z6rA:
11.00
5ef2H-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef2H-1z6rA:
undetectable
5ef2I-1z6rA:
undetectable		 5ef2H-1z6rA:
11.00
5ef2I-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5ef2J-1z6rA:
undetectable
5ef2K-1z6rA:
undetectable		 5ef2J-1z6rA:
11.00
5ef2K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5ef2A-1z6rA:
undetectable
5ef2K-1z6rA:
undetectable		 5ef2A-1z6rA:
11.00
5ef2K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.26A 5ef3B-1z6rA:
undetectable
5ef3C-1z6rA:
undetectable		 5ef3B-1z6rA:
11.00
5ef3C-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.29A 5ef3C-1z6rA:
undetectable
5ef3D-1z6rA:
undetectable		 5ef3C-1z6rA:
11.00
5ef3D-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.27A 5ef3H-1z6rA:
undetectable
5ef3I-1z6rA:
undetectable		 5ef3H-1z6rA:
11.00
5ef3I-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 9 THR A 200
SER A 209
GLY A 341
THR A 376
ILE A 340
 None
 1.30A 5ef3J-1z6rA:
undetectable
5ef3K-1z6rA:
undetectable		 5ef3J-1z6rA:
11.00
5ef3K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 GLY A 341
THR A 376
ILE A 340
THR A 200
SER A 209
 None
 1.27A 5ef3A-1z6rA:
undetectable
5ef3K-1z6rA:
undetectable		 5ef3A-1z6rA:
11.00
5ef3K-1z6rA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 5 TYR A 258
PRO A 168
GLY A 162
LEU A 242
 None
 1.00A 5eslA-1z6rA:
undetectable		 5eslA-1z6rA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 1z6r MLC PROTEIN
(Escherichia
coli) 		3 / 3 TRP A 199
ILE A 340
SER A 345
 None
 1.01A 5gqbA-1z6rA:
undetectable		 5gqbA-1z6rA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6r MLC PROTEIN
(Escherichia
coli) 		6 / 11 ILE A 128
GLN A 114
LEU A  99
LEU A 116
VAL A 164
LEU A 182
 None
 1.31A 5ji0A-1z6rA:
undetectable		 5ji0A-1z6rA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 ALA A  18
VAL A  21
LEU A  36
MET A  54
 None
 0.80A 5nujA-1z6rA:
undetectable		 5nujA-1z6rA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 ILE A  97
LEU A 116
ILE A  92
ILE A 151
 None
 0.70A 5numA-1z6rA:
undetectable		 5numA-1z6rA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 7 LEU A 265
LEU A 242
ILE A 325
GLY A 323
LEU A 326
 None
 1.34A 5vkqA-1z6rA:
undetectable
5vkqB-1z6rA:
undetectable		 5vkqA-1z6rA:
13.17
5vkqB-1z6rA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1z6r MLC PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 318
GLY A 319
GLY A 323
ILE A 245
ALA A 269
 None
 1.04A 5vm8B-1z6rA:
undetectable		 5vm8B-1z6rA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1z6r MLC PROTEIN
(Escherichia
coli) 		4 / 8 ILE A 151
VAL A 110
GLU A 112
SER A 113
 None
 0.90A 6fbvC-1z6rA:
0.8		 6fbvC-1z6rA:
18.34