SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		4 / 7 PRO A 769
LEU A 775
GLY A 776
LEU A 757
 None
 0.86A 1ya4B-1z6uA:
undetectable		 1ya4B-1z6uA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		3 / 3 GLY A 720
GLU A 688
ASN A 722
 None
 0.70A 1zq9A-1z6uA:
undetectable		 1zq9A-1z6uA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_D_BEZD2002_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		5 / 9 PHE A 731
LEU A 727
PHE A 723
LEU A 790
ASP A 703
 None
 1.38A 2ok6B-1z6uA:
undetectable
2ok6D-1z6uA:
undetectable		 2ok6B-1z6uA:
17.60
2ok6D-1z6uA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		5 / 10 PHE A 731
LEU A 727
PHE A 723
LEU A 790
ASP A 703
 None
 1.38A 2ok6A-1z6uA:
undetectable
2ok6H-1z6uA:
undetectable		 2ok6A-1z6uA:
17.60
2ok6H-1z6uA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		4 / 5 GLN A 697
THR A 693
THR A 789
HIS A 698
 None
 1.50A 3g1uC-1z6uA:
undetectable		 3g1uC-1z6uA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		5 / 12 PHE A 795
PHE A 794
LEU A 717
SER A 730
MET A 732
 None
 1.40A 4a83A-1z6uA:
undetectable		 4a83A-1z6uA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		5 / 12 PHE A 795
PHE A 794
LEU A 717
SER A 730
MET A 732
 None
 1.37A 4a84A-1z6uA:
undetectable		 4a84A-1z6uA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		3 / 3 ASN A 784
ASP A 703
ASN A 706
 None
 0.65A 4agaA-1z6uA:
undetectable		 4agaA-1z6uA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1z6u NP95-LIKE RING
FINGER PROTEIN
ISOFORM B
(Homo
sapiens) 		3 / 3 LEU A 699
PHE A 794
ILE A 700
 None
 0.68A 5dzk1-1z6uA:
undetectable
5dzkF-1z6uA:
undetectable
5dzkM-1z6uA:
undetectable		 5dzk1-1z6uA:
1.44
5dzkF-1z6uA:
20.89
5dzkM-1z6uA:
20.77