SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		3 / 3 LYS A 126
ASP A  66
ASN A  26
 GDP  A 180 (-3.2A)
GDP  A 180 ( 4.3A)
GDP  A 180 (-3.2A)
 1.16A 2bm9A-1z6yA:
2.7		 2bm9A-1z6yA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		5 / 11 LEU A  24
GLY A  28
ILE A  99
SER A  93
VAL A  90
 None
GDP  A 180 (-3.2A)
None
None
None
 1.18A 3gyqB-1z6yA:
undetectable		 3gyqB-1z6yA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		3 / 3 ILE A  88
PHE A  36
HIS A 153
 None
 0.67A 3h0aA-1z6yA:
undetectable		 3h0aA-1z6yA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		4 / 8 HIS A 150
ASP A 114
LEU A 115
ILE A  20
 None
 1.04A 4k0bA-1z6yA:
undetectable		 4k0bA-1z6yA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		4 / 8 HIS A 150
ASP A 114
LEU A 115
ILE A  20
 None
 1.02A 4l7iA-1z6yA:
undetectable		 4l7iA-1z6yA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5
(Homo
sapiens) 		3 / 3 TYR A  80
HIS A 112
MET A 109
 None
 1.08A 6af6A-1z6yA:
undetectable		 6af6A-1z6yA:
18.00