SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 1z77 TRANSCRIPTIONAL
REGULATOR (TETR
FAMILY)
(Thermotoga
maritima) 		4 / 4 VAL A 145
ALA A 150
LEU A 194
PHE A 153
 None
 1.20A 1q97B-1z77A:
undetectable		 1q97B-1z77A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1z77 TRANSCRIPTIONAL
REGULATOR (TETR
FAMILY)
(Thermotoga
maritima) 		4 / 8 VAL A 187
PHE A 158
TYR A 165
VAL A 184
 None
 1.02A 3fhxB-1z77A:
undetectable		 3fhxB-1z77A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1z77 TRANSCRIPTIONAL
REGULATOR (TETR
FAMILY)
(Thermotoga
maritima) 		3 / 3 VAL A 187
LYS A 195
MET A 198
 None
 0.99A 5nknA-1z77A:
undetectable		 5nknA-1z77A:
15.18