SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 4 HIS A 249
LEU A 388
LEU A 309
LEU A  99
 None
 1.08A 1a4lD-1z7dA:
2.3		 1a4lD-1z7dA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 4 HIS A 249
LEU A 388
LEU A 309
LEU A 100
 None
 1.22A 1a4lD-1z7dA:
2.3		 1a4lD-1z7dA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 12 ALA A 299
ALA A 298
LEU A 297
ILE A  79
LEU A  89
 None
 0.88A 2aclG-1z7dA:
undetectable		 2aclG-1z7dA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 6 CYH A 398
PRO A 386
LEU A 321
ILE A 390
 None
 1.02A 2q83B-1z7dA:
undetectable		 2q83B-1z7dA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 5 PHE A 325
SER A 336
PHE A  50
ILE A 338
 None
 1.21A 2v0mD-1z7dA:
undetectable		 2v0mD-1z7dA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 6 LEU A 121
THR A 117
LEU A 258
ASP A 255
 None
 1.07A 2wm3A-1z7dA:
3.2		 2wm3A-1z7dA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 8 HIS A  63
LEU A  96
LEU A 263
CYH A 302
 None
 1.04A 3lm8B-1z7dA:
undetectable
3lm8D-1z7dA:
undetectable		 3lm8B-1z7dA:
19.72
3lm8D-1z7dA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 10 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.21A 3lxiA-1z7dA:
undetectable		 3lxiA-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 11 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.19A 3lxiB-1z7dA:
undetectable		 3lxiB-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 11 GLY A 344
LEU A 384
LEU A 347
LEU A 329
LEU A 326
 None
 0.87A 3ndvA-1z7dA:
undetectable
3ndvB-1z7dA:
undetectable		 3ndvA-1z7dA:
22.55
3ndvB-1z7dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 11 LEU A 329
LEU A 326
GLY A 344
LEU A 384
LEU A 347
 None
 0.87A 3ndvA-1z7dA:
0.0
3ndvB-1z7dA:
0.0		 3ndvA-1z7dA:
22.55
3ndvB-1z7dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 11 GLY A 344
LEU A 384
LEU A 347
LEU A 329
LEU A 326
 None
 0.85A 3ndvC-1z7dA:
0.0
3ndvD-1z7dA:
0.0		 3ndvC-1z7dA:
22.55
3ndvD-1z7dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 11 LEU A 329
LEU A 326
GLY A 344
LEU A 384
LEU A 347
 None
 0.86A 3ndvC-1z7dA:
undetectable
3ndvD-1z7dA:
undetectable		 3ndvC-1z7dA:
22.55
3ndvD-1z7dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 7 TYR A 250
TYR A 178
CYH A 142
TYR A 214
 None
 1.48A 3peoF-1z7dA:
0.0		 3peoF-1z7dA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 10 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.20A 4c9nB-1z7dA:
undetectable		 4c9nB-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 9 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.21A 4c9pA-1z7dA:
undetectable		 4c9pA-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 10 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.22A 4c9pB-1z7dA:
undetectable		 4c9pB-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		3 / 3 LYS A 320
PRO A 324
LYS A 392
 None
 1.23A 4duzL-1z7dA:
0.6		 4duzL-1z7dA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		3 / 3 ILE A 132
ASP A 190
ARG A 123
 None
 0.67A 4pstA-1z7dA:
undetectable		 4pstA-1z7dA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		4 / 7 GLU A 199
ARG A 343
GLY A 206
GLY A 203
 None
 0.89A 4rdxA-1z7dA:
undetectable		 4rdxA-1z7dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 12 GLU A 187
GLU A 185
LEU A 184
GLU A 182
LEU A 181
 None
 1.08A 5nwvA-1z7dA:
undetectable		 5nwvA-1z7dA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		5 / 9 LEU A 215
VAL A 252
VAL A 247
ILE A 257
ASP A 255
 None
 1.21A 5yf9X-1z7dA:
undetectable		 5yf9X-1z7dA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1z7d ORNITHINE
AMINOTRANSFERASE
(Plasmodium
yoelii) 		3 / 3 TYR A  95
ALA A 272
LEU A 259
 None
 0.69A 6ag0C-1z7dA:
2.2		 6ag0C-1z7dA:
9.24