SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 GLU A  57
TYR A  83
PHE A  63
 None
 0.89A 1eqbB-1z7mA:
undetectable		 1eqbB-1z7mA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 GLU A  57
TYR A  83
PHE A  63
 None
 0.87A 1eqbA-1z7mA:
undetectable		 1eqbA-1z7mA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 GLU A  57
TYR A  83
PHE A  63
 None
 0.88A 1eqbD-1z7mA:
undetectable		 1eqbD-1z7mA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 GLU A  57
TYR A  83
PHE A  63
 None
 0.88A 1eqbC-1z7mA:
undetectable		 1eqbC-1z7mA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
ARG A 112
GLN A 126
GLU A 130
 None
 0.92A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
ARG A 112
GLU A 130
TYR A 268
 None
 0.98A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
ARG A 112
GLU A 130
TYR A 269
 None
 1.15A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
GLN A 126
GLU A 130
GLY A 288
 None
 0.80A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
GLU A 130
TYR A 269
GLY A 288
 None
 0.75A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 THR A  86
TYR A 106
GLU A 130
TYR A 269
GLY A 289
 None
 1.10A 1httA-1z7mA:
23.8		 1httA-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 ARG A 112
TYR A 268
TYR A 269
TYR A 291
GLY A 306
 None
 1.30A 1httB-1z7mA:
23.5		 1httB-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		7 / 12 THR A  86
ARG A 112
GLN A 126
GLU A 130
TYR A 269
TYR A 291
GLY A 306
 None
 1.10A 1httB-1z7mA:
23.5		 1httB-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		6 / 12 THR A  86
GLN A 126
GLU A 130
TYR A 269
GLY A 288
GLY A 306
 None
 0.69A 1httB-1z7mA:
23.5		 1httB-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLN A 126
GLU A 130
GLY A 288
GLY A 306
 None
 0.53A 1httC-1z7mA:
23.8		 1httC-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLN A 126
GLU A 130
TYR A 291
GLY A 306
 None
 1.00A 1httC-1z7mA:
23.8		 1httC-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
GLY A 288
GLY A 306
 None
 0.62A 1httC-1z7mA:
23.8		 1httC-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
TYR A 291
GLY A 306
 None
 1.15A 1httC-1z7mA:
23.8		 1httC-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 GLU A 130
TYR A 268
TYR A 269
GLY A 288
GLY A 306
 None
 0.77A 1httD-1z7mA:
23.5		 1httD-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
GLY A 288
GLY A 306
 None
 0.60A 1httD-1z7mA:
23.5		 1httD-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
GLY A 289
GLY A 306
 None
 1.29A 1httD-1z7mA:
23.5		 1httD-1z7mA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 CYH A 308
GLY A 288
TYR A 268
GLU A 130
 None
 1.00A 1jlfA-1z7mA:
2.0
1jlfB-1z7mA:
2.0		 1jlfA-1z7mA:
20.96
1jlfB-1z7mA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		4 / 7 LEU E  44
MET E 198
LEU E 202
MET E 181
 None
 1.01A 1linA-1z7mE:
undetectable		 1linA-1z7mE:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LEU A  87
GLU A 130
THR A 270
TYR A 268
 None
 1.42A 1qvuA-1z7mA:
undetectable		 1qvuA-1z7mA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.79A 1rtsB-1z7mA:
undetectable		 1rtsB-1z7mA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 TYR A 125
PHE A 111
ARG A  82
MET A  15
 None
 1.13A 1x8vA-1z7mA:
undetectable		 1x8vA-1z7mA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 5 LEU A 131
ILE A 143
LEU A 144
SER A 145
 None
 1.00A 2byoA-1z7mA:
undetectable		 2byoA-1z7mA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.75A 2eilP-1z7mA:
undetectable
2eilW-1z7mA:
undetectable		 2eilP-1z7mA:
20.44
2eilW-1z7mA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 PHE A  34
ARG A  31
SER A 105
GLY A 128
 None
 0.90A 2f7fA-1z7mA:
undetectable		 2f7fA-1z7mA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 LEU A 208
GLY A 210
LEU A 212
ILE A 215
LEU A 236
 None
 1.04A 2f8dA-1z7mA:
undetectable		 2f8dA-1z7mA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 10 LEU A 208
GLY A 210
LEU A 212
ILE A 215
LEU A 236
 None
 1.06A 2f8dB-1z7mA:
undetectable		 2f8dB-1z7mA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.82A 2tsrB-1z7mA:
undetectable		 2tsrB-1z7mA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 MET A 273
VAL A 150
GLU A 130
 None
 0.87A 2x9gA-1z7mA:
undetectable		 2x9gA-1z7mA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 8 LEU A 172
ILE A 215
LEU A 211
THR A 231
LEU A 236
 None
 1.18A 2xfhA-1z7mA:
undetectable		 2xfhA-1z7mA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.72A 3abkP-1z7mA:
undetectable
3abkW-1z7mA:
undetectable		 3abkP-1z7mA:
20.44
3abkW-1z7mA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		3 / 3 LYS E 136
ILE E  55
PHE E  57
 None
 0.90A 3j7zS-1z7mE:
undetectable
3j7za-1z7mE:
undetectable		 3j7zS-1z7mE:
22.66
3j7za-1z7mE:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 LYS A 167
ARG A 290
LYS A 249
 None
 1.39A 3okxA-1z7mA:
undetectable		 3okxA-1z7mA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		4 / 5 GLU E 138
GLY E 139
TYR E 117
ASP E 155
 None
 1.17A 3w9tD-1z7mE:
undetectable		 3w9tD-1z7mE:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.74A 3wg7P-1z7mA:
undetectable
3wg7W-1z7mA:
undetectable		 3wg7P-1z7mA:
20.44
3wg7W-1z7mA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ARG A  31
LEU A  30
MET A 311
TYR A 125
 None
 1.33A 3zmdA-1z7mA:
0.0
3zmdB-1z7mA:
0.0		 3zmdA-1z7mA:
19.65
3zmdB-1z7mA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 9 ARG A 103
ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 1.04A 4eb4C-1z7mA:
undetectable		 4eb4C-1z7mA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		4 / 7 ALA E 152
GLU E 130
TYR E 124
LEU E  96
 None
 0.98A 4iomA-1z7mE:
undetectable		 4iomA-1z7mE:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.77A 4iqqA-1z7mA:
undetectable		 4iqqA-1z7mA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.82A 4iqqD-1z7mA:
undetectable		 4iqqD-1z7mA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 THR A  86
GLU A 130
GLY A 288
GLY A 306
 None
 0.42A 4rdxA-1z7mA:
24.8		 4rdxA-1z7mA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 7 THR A  86
GLU A 130
TYR A 268
TYR A 291
GLY A 306
 None
 1.47A 4rdxA-1z7mA:
24.8		 4rdxA-1z7mA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 TYR A  39
ASN A  38
GLU A 142
GLU A 134
 None
 1.41A 4twdG-1z7mA:
undetectable
4twdH-1z7mA:
undetectable		 4twdG-1z7mA:
21.88
4twdH-1z7mA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		3 / 3 LYS A 254
ILE A 256
ILE A 163
 None
 0.53A 4y0qA-1z7mA:
undetectable		 4y0qA-1z7mA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LEU A 144
LEU A 286
PHE A 274
ILE A 257
 None
 1.03A 4y4dA-1z7mA:
undetectable		 4y4dA-1z7mA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LYS A 138
ARG A 103
GLY A 133
LEU A 131
 None
 1.07A 5bphA-1z7mA:
undetectable		 5bphA-1z7mA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		6 / 12 THR A  86
ARG A 112
GLN A 126
GLU A 130
TYR A 291
GLY A 306
 None
 1.11A 5e3iA-1z7mA:
23.7		 5e3iA-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLN A 126
GLU A 130
GLY A 288
GLY A 306
 None
 0.58A 5e3iA-1z7mA:
23.7		 5e3iA-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
GLY A 288
GLY A 306
 None
 0.61A 5e3iA-1z7mA:
23.7		 5e3iA-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 12 THR A  86
GLU A 130
TYR A 269
TYR A 291
GLY A 306
 None
 1.03A 5e3iA-1z7mA:
23.7		 5e3iA-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 ARG A 112
GLU A 130
TYR A 268
TYR A 291
GLY A 306
 None
 1.28A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 GLU A 130
TYR A 268
TYR A 269
GLY A 288
GLY A 306
 None
 0.75A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 GLU A 130
TYR A 268
TYR A 269
TYR A 291
GLY A 306
 None
 1.13A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		6 / 11 THR A  86
ARG A 112
GLN A 126
GLU A 130
TYR A 291
GLY A 306
 None
 1.12A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 THR A  86
GLN A 126
GLU A 130
GLY A 288
GLY A 306
 None
 0.61A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 THR A  86
GLU A 130
TYR A 269
GLY A 288
GLY A 306
 None
 0.63A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 THR A  86
GLU A 130
TYR A 269
GLY A 289
GLY A 306
 None
 1.34A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 THR A  86
GLU A 130
TYR A 269
TYR A 291
GLY A 306
 None
 1.06A 5e3iB-1z7mA:
23.8		 5e3iB-1z7mA:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.71A 5h3aA-1z7mA:
undetectable		 5h3aA-1z7mA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 PHE A 107
PHE A  47
SER A 105
VAL A  42
 None
 1.30A 5hesA-1z7mA:
undetectable		 5hesA-1z7mA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.70A 5iy5C-1z7mA:
undetectable
5iy5J-1z7mA:
undetectable		 5iy5C-1z7mA:
20.11
5iy5J-1z7mA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 9 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.10A 5lg3B-1z7mE:
0.0		 5lg3B-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 9 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.07A 5lg3C-1z7mE:
0.0		 5lg3C-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 9 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.08A 5lg3D-1z7mE:
0.0		 5lg3D-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 12 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.08A 5lg3E-1z7mE:
undetectable		 5lg3E-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 10 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.11A 5lg3F-1z7mE:
undetectable		 5lg3F-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 10 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.10A 5lg3H-1z7mE:
undetectable		 5lg3H-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis) 		5 / 12 PHE E  57
VAL E  68
THR E  72
ASN E  76
ILE E  55
 None
 1.10A 5lg3J-1z7mE:
undetectable		 5lg3J-1z7mE:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.84A 5nooD-1z7mA:
undetectable		 5nooD-1z7mA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 6 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.69A 5x19P-1z7mA:
undetectable		 5x19P-1z7mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 5 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.73A 5x1bP-1z7mA:
undetectable		 5x1bP-1z7mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.79A 5x5qC-1z7mA:
undetectable		 5x5qC-1z7mA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.81A 5x5qD-1z7mA:
undetectable		 5x5qD-1z7mA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 8 ILE A 129
GLY A 288
PHE A 307
TYR A 268
 None
 0.81A 5x5qF-1z7mA:
undetectable		 5x5qF-1z7mA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		4 / 7 LEU A 236
PHE A 240
PHE A 168
LEU A 172
 None
 0.75A 5z84C-1z7mA:
undetectable
5z84J-1z7mA:
undetectable		 5z84C-1z7mA:
20.44
5z84J-1z7mA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 9 LEU A 172
GLY A 210
LEU A 212
THR A 231
VAL A 228
 None
 1.34A 6czmA-1z7mA:
1.4
6czmB-1z7mA:
undetectable		 6czmA-1z7mA:
23.33
6czmB-1z7mA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 9 LEU A 172
GLY A 210
LEU A 212
THR A 231
VAL A 228
 None
 1.20A 6czmD-1z7mA:
1.5
6czmE-1z7mA:
undetectable		 6czmD-1z7mA:
23.33
6czmE-1z7mA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
(Lactococcus
lactis) 		5 / 11 ILE A  26
LEU A  23
MET A  15
THR A  16
MET A 311
 None
 1.21A 6hupA-1z7mA:
0.0
6hupB-1z7mA:
0.0		 6hupA-1z7mA:
14.95
6hupB-1z7mA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis;
Lactococcus
lactis) 		4 / 6 ASP E  74
TYR E  81
GLU E  83
ASP A 191
 None
 1.34A 6mn5A-1z7mE:
undetectable		 6mn5A-1z7mE:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT
ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Lactococcus
lactis;
Lactococcus
lactis) 		4 / 6 ASP E  74
TYR E  81
GLU E  83
ASP A 191
 None
 1.30A 6mn5C-1z7mE:
undetectable		 6mn5C-1z7mE:
15.17