SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 10 LEU 2 126
VAL 2 210
ILE 2 108
TYR 2 106
LEU 2  66
 None
 1.06A 1cqpA-1z7s2:
undetectable
1cqpB-1z7s2:
undetectable		 1cqpA-1z7s2:
22.22
1cqpB-1z7s2:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		6 / 12 GLY 2 188
ALA 2 190
ILE 2 127
VAL 2 230
GLY 2 123
ILE 2 197
 None
 1.39A 1hshA-1z7s2:
undetectable		 1hshA-1z7s2:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		4 / 6 TRP 2  78
VAL 2  69
ILE 2 249
LEU 2 234
 None
 1.27A 1j96A-1z7s2:
undetectable		 1j96A-1z7s2:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		6 / 12 GLY 2 188
ALA 2 187
ILE 2 127
VAL 2 230
GLY 2 123
ILE 2 197
 None
 1.34A 2rkgA-1z7s2:
undetectable		 2rkgA-1z7s2:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		4 / 7 ILE 2 229
GLY 2 228
PHE 2 130
PHE 2 157
 None
 0.87A 2y7wC-1z7s2:
undetectable		 2y7wC-1z7s2:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		4 / 7 ALA 2  31
SER 2 205
THR 2 207
VAL 2 209
 None
 0.98A 3d2tA-1z7s2:
undetectable		 3d2tA-1z7s2:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		4 / 6 ALA 2  31
SER 2 205
THR 2 207
VAL 2 209
 None
 0.93A 3d2tB-1z7s2:
undetectable		 3d2tB-1z7s2:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		3 / 3 MET 2 256
MET 2  91
PHE 2  63
 None
 1.31A 3gn8A-1z7s2:
undetectable		 3gn8A-1z7s2:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		3 / 3 PRO 2  53
THR 2  54
LEU 2 263
 None
 0.40A 3ttrA-1z7s2:
undetectable		 3ttrA-1z7s2:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 12 GLY 2 188
ILE 2 127
VAL 2 230
GLY 2 123
ILE 2 197
 None
 0.91A 3ucbB-1z7s2:
undetectable		 3ucbB-1z7s2:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 10 ALA 2 187
VAL 2 230
GLY 2 123
ILE 2 197
VAL 2 192
 None
 1.06A 4j5jB-1z7s2:
undetectable		 4j5jB-1z7s2:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.56A 4xmfA-1z7s2:
undetectable		 4xmfA-1z7s2:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		3 / 3 ALA 2 254
TYR 2  64
PRO 2  56
 None
 0.63A 4zdyA-1z7s2:
undetectable		 4zdyA-1z7s2:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		4 / 4 VAL 2 110
ALA 2 206
ASN 2 203
GLN 2 196
 None
 1.44A 4zgfA-1z7s2:
undetectable		 4zgfA-1z7s2:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 11 LEU 2 186
ALA 2 187
LEU 2 181
LEU 2 177
GLY 2  77
 None
 1.16A 5dxgB-1z7s2:
undetectable		 5dxgB-1z7s2:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 12 GLY 2 188
ALA 2 187
ASP 2 178
GLY 2 123
ILE 2 127
 None
 0.88A 5e5jB-1z7s2:
undetectable		 5e5jB-1z7s2:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 12 LEU 2 186
ALA 2 187
LEU 2 181
LEU 2 177
GLY 2  77
 None
 1.11A 5gtrA-1z7s2:
undetectable		 5gtrA-1z7s2:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1z7s HUMAN COXSACKIEVIRUS
A21
(Enterovirus
C) 		5 / 10 VAL 2 124
GLY 2 123
ALA 2 206
ASN 2 199
ASN 2 203
 None
 1.10A 5x6yB-1z7s2:
undetectable		 5x6yB-1z7s2:
16.62