SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
5 / 12 MET 3 165
GLY 3 211
LEU 3  94
CYH 3 191
ILE 3 153
None
1.23A 1p93B-1z7z3:
undetectable
1p93B-1z7z3:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 ASN 3 104
HIS 3  96
SER 3  95
ARG 3  93
None
1.30A 1u1jA-1z7z3:
undetectable
1u1jA-1z7z3:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.85A 1v55C-1z7z3:
undetectable
1v55N-1z7z3:
undetectable
1v55P-1z7z3:
undetectable
1v55C-1z7z3:
23.67
1v55N-1z7z3:
17.82
1v55P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 5 PRO I  28
LEU I  31
GLY I  32
LYS I  50
None
1.33A 1ya4C-1z7zI:
undetectable
1ya4C-1z7zI:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 7 PHE I 185
GLU I 220
GLN I 183
TYR I 180
None
1.41A 2aoxB-1z7zI:
0.0
2aoxB-1z7zI:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 5 GLU I 416
PRO I 390
ILE I 414
GLY I 415
None
0.92A 2qeuA-1z7zI:
undetectable
2qeuC-1z7zI:
undetectable
2qeuA-1z7zI:
14.77
2qeuC-1z7zI:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
5 / 9 PRO 3  88
LEU 3  94
LEU 3  86
ALA 3 167
PHE 3 115
None
1.24A 2vcvD-1z7z3:
undetectable
2vcvD-1z7z3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
5 / 9 PRO 3  88
LEU 3  94
LEU 3  86
ALA 3 167
PHE 3 115
None
1.25A 2vcvE-1z7z3:
undetectable
2vcvE-1z7z3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
5 / 8 LEU 3  99
PRO 3  88
LEU 3  86
ALA 3 167
PHE 3 115
None
1.48A 2vcvF-1z7z3:
undetectable
2vcvF-1z7z3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
5 / 9 PRO 3  88
LEU 3  94
LEU 3  86
ALA 3 167
PHE 3 115
None
1.23A 2vcvH-1z7z3:
undetectable
2vcvH-1z7z3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)
1z7z HUMAN COXSACKIEVIRUS
A21
INTERCELLULAR
ADHESION MOLECULE-1

(Enterovirus
C;
Homo
sapiens)
3 / 3 ARG 3 180
GLU 1 277
SER I  74
None
0.94A 2xkkA-1z7z3:
undetectable
2xkkC-1z7z3:
undetectable
2xkkA-1z7z3:
14.93
2xkkC-1z7z3:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 TYR 3 106
MET 3  98
ILE 3 102
SER 1 174
None
1.23A 2xytI-1z7z3:
undetectable
2xytI-1z7z3:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.84A 2y69C-1z7z3:
undetectable
2y69N-1z7z3:
undetectable
2y69P-1z7z3:
undetectable
2y69C-1z7z3:
23.67
2y69N-1z7z3:
17.82
2y69P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.95A 3ablA-1z7z3:
undetectable
3ablC-1z7z3:
undetectable
3ablP-1z7z3:
undetectable
3ablA-1z7z3:
17.82
3ablC-1z7z3:
23.67
3ablP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.86A 3ablC-1z7z3:
undetectable
3ablN-1z7z3:
undetectable
3ablP-1z7z3:
undetectable
3ablC-1z7z3:
23.67
3ablN-1z7z3:
17.82
3ablP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.93A 3abmA-1z7z3:
undetectable
3abmC-1z7z3:
undetectable
3abmP-1z7z3:
undetectable
3abmA-1z7z3:
17.82
3abmC-1z7z3:
23.67
3abmP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.85A 3asnC-1z7z3:
undetectable
3asnN-1z7z3:
undetectable
3asnP-1z7z3:
undetectable
3asnC-1z7z3:
23.67
3asnN-1z7z3:
17.82
3asnP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.87A 3asoA-1z7z3:
undetectable
3asoC-1z7z3:
undetectable
3asoP-1z7z3:
undetectable
3asoA-1z7z3:
17.82
3asoC-1z7z3:
23.67
3asoP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.85A 3asoC-1z7z3:
undetectable
3asoN-1z7z3:
undetectable
3asoP-1z7z3:
undetectable
3asoC-1z7z3:
23.67
3asoN-1z7z3:
17.82
3asoP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 PHE 3  82
ILE 3 197
TYR 3 193
THR 3 195
None
0.89A 3gssA-1z7z3:
undetectable
3gssA-1z7z3:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 PHE 3  82
ILE 3 197
TYR 3 193
THR 3 195
None
0.91A 3gssB-1z7z3:
undetectable
3gssB-1z7z3:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 7 VAL I 445
TRP I 382
GLU I 416
PRO I 413
None
1.29A 3hs4A-1z7zI:
undetectable
3hs4A-1z7zI:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 TYR 1 204
GLU 3 185
LEU 1 226
ASN 1 230
None
1.12A 3k8mA-1z7z1:
undetectable
3k8mA-1z7z1:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 6 TYR 3 106
MET 3  98
ILE 3 102
SER 1 174
None
1.08A 3pmzD-1z7z3:
undetectable
3pmzD-1z7z3:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 8 LEU I 106
GLN I  98
TYR I 180
PHE I 157
None
1.30A 3po7A-1z7zI:
undetectable
3po7A-1z7zI:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
5 / 9 ALA I 245
PHE I 243
ILE I 266
GLU I 273
THR I 274
None
1.46A 3rukC-1z7zI:
0.0
3rukC-1z7zI:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.92A 3wg7A-1z7z3:
undetectable
3wg7C-1z7z3:
undetectable
3wg7P-1z7z3:
undetectable
3wg7A-1z7z3:
17.82
3wg7C-1z7z3:
23.67
3wg7P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.89A 3wg7C-1z7z3:
undetectable
3wg7N-1z7z3:
undetectable
3wg7P-1z7z3:
undetectable
3wg7C-1z7z3:
23.67
3wg7N-1z7z3:
17.82
3wg7P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.93A 3x2qA-1z7z3:
undetectable
3x2qC-1z7z3:
undetectable
3x2qP-1z7z3:
undetectable
3x2qA-1z7z3:
17.82
3x2qC-1z7z3:
23.67
3x2qP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.82A 3x2qC-1z7z3:
undetectable
3x2qN-1z7z3:
undetectable
3x2qP-1z7z3:
undetectable
3x2qC-1z7z3:
23.67
3x2qN-1z7z3:
17.82
3x2qP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 ILE 1 248
GLU 1 135
TYR 1 150
VAL 1 254
None
1.09A 4a97A-1z7z1:
undetectable
4a97A-1z7z1:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 ILE 1 248
GLU 1 135
TYR 1 150
VAL 1 254
None
1.11A 4a97H-1z7z1:
undetectable
4a97H-1z7z1:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 SER 1 251
LYS 1  97
SER 1  86
THR 1  88
None
0.95A 4ikjA-1z7z1:
undetectable
4ikjB-1z7z1:
undetectable
4ikjA-1z7z1:
17.99
4ikjB-1z7z1:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LYS 1  97
SER 1  86
THR 1  88
SER 1 251
None
0.83A 4ikkA-1z7z1:
undetectable
4ikkB-1z7z1:
undetectable
4ikkA-1z7z1:
17.99
4ikkB-1z7z1:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 SER 1 251
LYS 1  97
SER 1  86
THR 1  88
None
0.97A 4iklA-1z7z1:
undetectable
4iklB-1z7z1:
undetectable
4iklA-1z7z1:
17.99
4iklB-1z7z1:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 7 VAL I 265
ALA I 221
LEU I 225
ASP I 213
None
0.76A 4l9iA-1z7zI:
undetectable
4l9iA-1z7zI:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
5 / 10 ASN I  56
VAL I  17
LEU I  11
LEU I  80
VAL I  82
None
1.13A 4po0A-1z7zI:
undetectable
4po0A-1z7zI:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 6 GLU 1 135
THR 1 250
LEU 1  87
GLN 1 148
None
1.46A 4qztA-1z7z1:
undetectable
4qztA-1z7z1:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 4 THR I  23
GLY I  72
ASP I  71
SER I  67
None
1.31A 4rfqA-1z7zI:
undetectable
4rfqA-1z7zI:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 5 ILE 3  49
HIS 3 229
TYR 3 106
VAL 3 221
None
1.29A 4s0vA-1z7z3:
undetectable
4s0vA-1z7z3:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.92A 5b1aA-1z7z3:
undetectable
5b1aC-1z7z3:
undetectable
5b1aP-1z7z3:
undetectable
5b1aA-1z7z3:
17.82
5b1aC-1z7z3:
23.67
5b1aP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.92A 5b1bA-1z7z3:
undetectable
5b1bC-1z7z3:
undetectable
5b1bP-1z7z3:
undetectable
5b1bA-1z7z3:
17.82
5b1bC-1z7z3:
23.67
5b1bP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.89A 5b3sA-1z7z3:
undetectable
5b3sC-1z7z3:
undetectable
5b3sP-1z7z3:
undetectable
5b3sA-1z7z3:
17.82
5b3sC-1z7z3:
23.67
5b3sP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 7 ALA I 155
TYR I 180
VAL I 148
HIS I 153
None
1.19A 5ecnA-1z7zI:
undetectable
5ecnA-1z7zI:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo
sapiens)
4 / 4 THR I 184
LEU I 182
HIS I 152
GLY I 154
None
1.19A 5gwyA-1z7zI:
undetectable
5gwyA-1z7zI:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.89A 5iy5C-1z7z3:
undetectable
5iy5N-1z7z3:
undetectable
5iy5P-1z7z3:
undetectable
5iy5C-1z7z3:
23.49
5iy5N-1z7z3:
17.82
5iy5P-1z7z3:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.88A 5w97A-1z7z3:
undetectable
5w97C-1z7z3:
undetectable
5w97c-1z7z3:
undetectable
5w97A-1z7z3:
17.82
5w97C-1z7z3:
23.67
5w97c-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.91A 5w97C-1z7z3:
undetectable
5w97a-1z7z3:
undetectable
5w97c-1z7z3:
undetectable
5w97C-1z7z3:
23.67
5w97a-1z7z3:
17.82
5w97c-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.94A 5wauA-1z7z3:
undetectable
5wauC-1z7z3:
undetectable
5wauc-1z7z3:
undetectable
5wauA-1z7z3:
17.82
5wauC-1z7z3:
23.67
5wauc-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.92A 5wauC-1z7z3:
undetectable
5waua-1z7z3:
undetectable
5wauc-1z7z3:
undetectable
5wauC-1z7z3:
23.67
5waua-1z7z3:
17.82
5wauc-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.98A 5x19A-1z7z3:
undetectable
5x19C-1z7z3:
undetectable
5x19P-1z7z3:
undetectable
5x19A-1z7z3:
17.82
5x19C-1z7z3:
23.67
5x19P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
1.00A 5x1bA-1z7z3:
undetectable
5x1bC-1z7z3:
undetectable
5x1bP-1z7z3:
undetectable
5x1bA-1z7z3:
17.82
5x1bC-1z7z3:
23.67
5x1bP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.91A 5x1fA-1z7z3:
undetectable
5x1fC-1z7z3:
undetectable
5x1fP-1z7z3:
undetectable
5x1fA-1z7z3:
17.82
5x1fC-1z7z3:
23.67
5x1fP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.92A 5xdqA-1z7z3:
undetectable
5xdqC-1z7z3:
undetectable
5xdqP-1z7z3:
undetectable
5xdqA-1z7z3:
17.82
5xdqC-1z7z3:
23.67
5xdqP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.87A 5xdqC-1z7z3:
undetectable
5xdqN-1z7z3:
undetectable
5xdqP-1z7z3:
undetectable
5xdqC-1z7z3:
23.67
5xdqN-1z7z3:
17.82
5xdqP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.88A 5xdxC-1z7z3:
undetectable
5xdxN-1z7z3:
undetectable
5xdxP-1z7z3:
undetectable
5xdxC-1z7z3:
23.76
5xdxN-1z7z3:
17.82
5xdxP-1z7z3:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)
1z7z HUMAN COXSACKIEVIRUS
A21
HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C;
Enterovirus
C)
4 / 5 HIS 3 108
TYR 1 200
GLY 1 195
TYR 1 193
None
1.33A 5yodH-1z7z3:
undetectable
5yodH-1z7z3:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.91A 5z84A-1z7z3:
undetectable
5z84C-1z7z3:
undetectable
5z84P-1z7z3:
undetectable
5z84A-1z7z3:
17.82
5z84C-1z7z3:
23.67
5z84P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.89A 5z84C-1z7z3:
undetectable
5z84N-1z7z3:
undetectable
5z84P-1z7z3:
undetectable
5z84C-1z7z3:
23.67
5z84N-1z7z3:
17.82
5z84P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.90A 5z85A-1z7z3:
undetectable
5z85C-1z7z3:
undetectable
5z85P-1z7z3:
undetectable
5z85A-1z7z3:
17.82
5z85C-1z7z3:
23.67
5z85P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.87A 5z85C-1z7z3:
undetectable
5z85N-1z7z3:
undetectable
5z85P-1z7z3:
undetectable
5z85C-1z7z3:
23.67
5z85N-1z7z3:
17.82
5z85P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.90A 5z86A-1z7z3:
undetectable
5z86C-1z7z3:
undetectable
5z86P-1z7z3:
undetectable
5z86A-1z7z3:
17.82
5z86C-1z7z3:
23.67
5z86P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.88A 5z86C-1z7z3:
undetectable
5z86N-1z7z3:
undetectable
5z86P-1z7z3:
undetectable
5z86C-1z7z3:
23.67
5z86N-1z7z3:
17.82
5z86P-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.89A 5zcoA-1z7z3:
undetectable
5zcoC-1z7z3:
undetectable
5zcoP-1z7z3:
undetectable
5zcoA-1z7z3:
17.82
5zcoC-1z7z3:
23.67
5zcoP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.88A 5zcoC-1z7z3:
undetectable
5zcoN-1z7z3:
undetectable
5zcoP-1z7z3:
undetectable
5zcoC-1z7z3:
23.67
5zcoN-1z7z3:
17.82
5zcoP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.92A 5zcpA-1z7z3:
undetectable
5zcpC-1z7z3:
undetectable
5zcpP-1z7z3:
undetectable
5zcpA-1z7z3:
17.82
5zcpC-1z7z3:
23.67
5zcpP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.90A 5zcpC-1z7z3:
undetectable
5zcpN-1z7z3:
undetectable
5zcpP-1z7z3:
undetectable
5zcpC-1z7z3:
23.67
5zcpN-1z7z3:
17.82
5zcpP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.91A 5zcqA-1z7z3:
undetectable
5zcqC-1z7z3:
undetectable
5zcqP-1z7z3:
undetectable
5zcqA-1z7z3:
17.82
5zcqC-1z7z3:
23.67
5zcqP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 8 LEU 3 224
HIS 3  96
ASP 3 226
THR 3 227
None
0.94A 6nknC-1z7z3:
undetectable
6nknN-1z7z3:
undetectable
6nknP-1z7z3:
undetectable
6nknC-1z7z3:
23.67
6nknN-1z7z3:
17.82
6nknP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 7 HIS 3  96
ASP 3 226
THR 3 227
LEU 3 224
None
0.95A 6nmfA-1z7z3:
undetectable
6nmfC-1z7z3:
undetectable
6nmfP-1z7z3:
undetectable
6nmfA-1z7z3:
17.82
6nmfC-1z7z3:
23.67
6nmfP-1z7z3:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus
C)
4 / 5 LEU 3 129
GLN 3 194
PHE 3 192
PHE 3 117
None
1.13A 6nmpP-1z7z3:
undetectable
6nmpW-1z7z3:
undetectable
6nmpP-1z7z3:
23.67
6nmpW-1z7z3:
14.53