SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 9 ALA A 175
ASP A 232
GLY A 101
ILE A 102
ILE A 210
 None
 1.15A 1hpvB-1z82A:
undetectable		 1hpvB-1z82A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 LEU A  98
ILE A  55
LEU A  72
VAL A  95
VAL A  28
 None
 1.21A 1hrkA-1z82A:
undetectable		 1hrkA-1z82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 LEU A 152
PHE A 224
ALA A 175
ALA A 228
LEU A 125
 None
 1.40A 1kt5A-1z82A:
undetectable		 1kt5A-1z82A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 LEU A  98
ILE A  55
LEU A  72
VAL A  95
VAL A  28
 None
 1.17A 2po7A-1z82A:
2.2		 2po7A-1z82A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 7 GLU A 112
GLY A 107
PHE A 213
ILE A 174
 None
 0.81A 2qmzA-1z82A:
5.1
2qmzB-1z82A:
5.1		 2qmzA-1z82A:
21.41
2qmzB-1z82A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 4 ARG A 109
GLY A 101
GLU A 173
SER A 291
 None
 1.32A 2xctS-1z82A:
undetectable
2xctU-1z82A:
1.8		 2xctS-1z82A:
19.11
2xctU-1z82A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 4 ARG A 109
GLY A 107
GLU A 112
SER A 291
 None
 1.34A 2xctS-1z82A:
undetectable
2xctU-1z82A:
1.8		 2xctS-1z82A:
19.11
2xctU-1z82A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 8 LEU A  72
ILE A  74
LEU A   8
LEU A  88
 None
 0.74A 2xfhA-1z82A:
undetectable		 2xfhA-1z82A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 11 GLY A 187
ALA A 183
ILE A 188
PHE A 247
ALA A 252
 None
None
MRD  A 601 (-3.8A)
None
None
 1.08A 3nmuB-1z82A:
1.4
3nmuJ-1z82A:
4.3		 3nmuB-1z82A:
23.16
3nmuJ-1z82A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 5 PHE A 216
ILE A 286
PHE A 213
PHE A 217
 None
 1.09A 3owxB-1z82A:
4.9		 3owxB-1z82A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 ILE A 286
ALA A 211
PHE A 213
ILE A 102
ILE A 280
 None
 0.75A 4kjjA-1z82A:
undetectable		 4kjjA-1z82A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 ILE A 286
ALA A 211
PHE A 213
ILE A 102
ILE A 280
 None
 0.81A 4pssA-1z82A:
undetectable		 4pssA-1z82A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 LEU A 189
ILE A 182
ILE A 290
VAL A 294
VAL A 298
 MRD  A 601 (-4.2A)
None
None
MRD  A 601 (-4.2A)
None
 0.92A 4y0pA-1z82A:
undetectable		 4y0pA-1z82A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		4 / 7 VAL A 170
GLU A 173
ASN A 284
ILE A 286
 None
 1.17A 5jh7C-1z82A:
undetectable		 5jh7C-1z82A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		6 / 12 GLY A 226
THR A 143
ILE A 207
GLY A 171
ALA A 175
ILE A 210
 None
 1.26A 5kb6A-1z82A:
3.5		 5kb6A-1z82A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		3 / 3 ALA A 276
VAL A 298
TYR A 295
 None
 0.61A 5zmqH-1z82A:
undetectable		 5zmqH-1z82A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1z82 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Thermotoga
maritima) 		5 / 12 TYR A 122
VAL A  28
LEU A 152
PHE A  17
LEU A 125
 None
 1.30A 6a93B-1z82A:
undetectable		 6a93B-1z82A:
22.58