SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		5 / 12 VAL A 173
LEU A 144
GLY A 175
PRO A 176
SER A 181
 None
None
None
CL  A 223 (-4.5A)
None
 1.48A 1fdsA-1z85A:
3.0		 1fdsA-1z85A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		4 / 6 LEU A 210
LEU A 166
LEU A 162
ILE A 151
 None
 0.99A 1z95A-1z85A:
undetectable		 1z95A-1z85A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		4 / 5 LEU A 188
THR A 192
HIS A 105
LEU A 141
 None
 1.06A 3ce6D-1z85A:
2.5		 3ce6D-1z85A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		4 / 8 PHE A   5
ILE A  35
PHE A  16
ALA A  21
 None
 0.81A 3me6B-1z85A:
undetectable		 3me6B-1z85A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		5 / 12 ARG A  86
VAL A 172
ILE A 215
GLY A 213
ILE A 209
 None
 1.04A 4njuC-1z85A:
undetectable		 4njuC-1z85A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		4 / 7 LEU A 210
LEU A 166
LEU A 162
ILE A 151
 None
 1.03A 4okwA-1z85A:
undetectable		 4okwA-1z85A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1z85 HYPOTHETICAL PROTEIN
TM1380
(Thermotoga
maritima) 		5 / 12 ILE A  91
PHE A 104
LEU A 141
PHE A 107
LEU A 153
 None
 1.27A 5xxiA-1z85A:
undetectable		 5xxiA-1z85A:
20.00