SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JIP_A_KTNA801_1 (CYTOCHROME P450 107A1)	1z87	ALPHA-1-SYNTROPHIN (Mus musculus)	5 / 12	GLY A 263 THR A 264 LEU A 33 ALA A 255 LEU A 40	GLY A 263 ( 0.0A) THR A 264 ( 0.8A) LEU A 33 ( 0.6A) ALA A 255 ( 0.0A) LEU A 40 ( 0.6A)	1.32A	1jipA-1z87A: undetectable	1jipA-1z87A: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BU8_A_TF4A1379_1 (PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2)	1z87	ALPHA-1-SYNTROPHIN (Mus musculus)	4 / 8	LEU A 123 ILE A 129 ILE A 94 ILE A 96	LEU A 123 ( 0.6A) ILE A 129 ( 0.6A) ILE A 94 ( 0.6A) ILE A 96 ( 0.6A)	0.84A	2bu8A-1z87A: undetectable	2bu8A-1z87A: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_X_BEZX801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 BEZ-LEU-LEU)	1z87	ALPHA-1-SYNTROPHIN (Mus musculus)	4 / 5	ILE A 96 GLY A 126 ILE A 94 LEU A 107	ILE A 96 ( 0.6A) GLY A 126 ( 0.0A) ILE A 94 ( 0.6A) LEU A 107 ( 0.6A)	0.88A	5dzki-1z87A: undetectable 5dzkj-1z87A: undetectable 5dzkx-1z87A: undetectable	5dzki-1z87A: 22.18 5dzkj-1z87A: 22.18 5dzkx-1z87A: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JIP_A_KTNA801_1","CYTOCHROME P450 107A1","1z87","ALPHA-1-SYNTROPHIN","Mus musculus",5,"GLY A 263;THR A 264;LEU A  33;ALA A 255;LEU A  40","GLY A 263 ( 0.0A);THR A 264 ( 0.8A);LEU A  33 ( 0.6A);ALA A 255 ( 0.0A);LEU A  40 ( 0.6A)","1.32A","1jipA-1z87A:undetectable","1jipA-1z87A:22.54"],["2BU8_A_TF4A1379_1","PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2","1z87","ALPHA-1-SYNTROPHIN","Mus musculus",4,"LEU A 123;ILE A 129;ILE A  94;ILE A  96","LEU A 123 ( 0.6A);ILE A 129 ( 0.6A);ILE A  94 ( 0.6A);ILE A  96 ( 0.6A)","0.84A","2bu8A-1z87A:undetectable","2bu8A-1z87A:20.72"],["5DZK_X_BEZX801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;BEZ-LEU-LEU","1z87","ALPHA-1-SYNTROPHIN","Mus musculus",4,"ILE A  96;GLY A 126;ILE A  94;LEU A 107","ILE A  96 ( 0.6A);GLY A 126 ( 0.0A);ILE A  94 ( 0.6A);LEU A 107 ( 0.6A)","0.88A","5dzki-1z87A:undetectable;5dzkj-1z87A:undetectable;5dzkx-1z87A:undetectable","5dzki-1z87A:22.18;5dzkj-1z87A:22.18;5dzkx-1z87A:16.67"]]