SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1z8y SPIKE GLYCOPROTEIN
E1
(Sindbis
virus) 		4 / 7 THR A 141
THR A 140
SER A 156
VAL A 161
 None
 1.21A 1tv8A-1z8yA:
undetectable		 1tv8A-1z8yA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1z8y SPIKE GLYCOPROTEIN
E1
(Sindbis
virus) 		4 / 8 THR A 141
THR A 140
SER A 156
VAL A 161
 None
 1.17A 2fb2A-1z8yA:
undetectable		 2fb2A-1z8yA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1z8y SPIKE GLYCOPROTEIN
E1
(Sindbis
virus) 		5 / 11 ILE A 214
GLY A 193
ALA A 215
LEU A 213
VAL A 108
 None
 1.26A 5hw4B-1z8yA:
undetectable		 5hw4B-1z8yA:
21.71