SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1z94 CONSERVED
HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 7 ILE A 117
PHE A  56
PHE A  67
GLY A  93
 None
 1.05A 3em0B-1z94A:
3.0		 3em0B-1z94A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 1z94 CONSERVED
HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		6 / 10 ALA A  21
ASP A  24
GLY A  77
PRO A  14
ALA A  13
VAL A 141
 None
 1.49A 3t3cB-1z94A:
undetectable		 3t3cB-1z94A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1z94 CONSERVED
HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ALA A  27
LEU A 137
LEU A 110
LEU A 101
ILE A  99
 None
 0.93A 3uvvA-1z94A:
undetectable		 3uvvA-1z94A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z94 CONSERVED
HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 8 LEU A  74
TRP A 130
TYR A  82
HIS A   8
 None
 1.22A 3wg7C-1z94A:
undetectable
3wg7N-1z94A:
undetectable
3wg7P-1z94A:
undetectable		 3wg7C-1z94A:
20.31
3wg7N-1z94A:
13.48
3wg7P-1z94A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1z94 CONSERVED
HYPOTHETICAL PROTEIN
(Chromobacterium
violaceum) 		4 / 8 TRP A 130
TYR A  82
HIS A   8
LEU A  74
 None
 1.07A 5x19A-1z94A:
undetectable
5x19C-1z94A:
undetectable
5x19P-1z94A:
undetectable		 5x19A-1z94A:
13.48
5x19C-1z94A:
20.31
5x19P-1z94A:
20.31