SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)
1z9f SINGLE-STRAND
BINDING PROTEIN

(Thermotoga
maritima)
3 / 3 ALA A  65
THR A  57
PHE A 106
None
0.63A 2c6nB-1z9fA:
undetectable
2c6nB-1z9fA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)
1z9f SINGLE-STRAND
BINDING PROTEIN

(Thermotoga
maritima)
5 / 11 GLY A  11
VAL A  99
ILE A   7
THR A  57
ILE A  55
None
0.97A 4njvC-1z9fA:
undetectable
4njvC-1z9fA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)
1z9f SINGLE-STRAND
BINDING PROTEIN

(Thermotoga
maritima)
3 / 3 ASP A 108
LEU A  13
GLY A  72
None
0.57A 4xmfA-1z9fA:
undetectable
4xmfA-1z9fA:
16.40