SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.11A 1zzrA-1z9mA:
undetectable
1zzrB-1z9mA:
undetectable		 1zzrA-1z9mA:
17.71
1zzrB-1z9mA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.13A 1zzrA-1z9mA:
undetectable
1zzrB-1z9mA:
undetectable		 1zzrA-1z9mA:
17.71
1zzrB-1z9mA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.12A 1zzuA-1z9mA:
undetectable
1zzuB-1z9mA:
undetectable		 1zzuA-1z9mA:
17.71
1zzuB-1z9mA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.11A 1zzuA-1z9mA:
undetectable
1zzuB-1z9mA:
undetectable		 1zzuA-1z9mA:
17.71
1zzuB-1z9mA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.10A 3dqrA-1z9mA:
undetectable
3dqrB-1z9mA:
undetectable		 3dqrA-1z9mA:
17.61
3dqrB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.12A 3dqrA-1z9mA:
undetectable
3dqrB-1z9mA:
undetectable		 3dqrA-1z9mA:
17.61
3dqrB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.10A 3jx2A-1z9mA:
undetectable
3jx2B-1z9mA:
undetectable		 3jx2A-1z9mA:
17.61
3jx2B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.09A 3jx2A-1z9mA:
undetectable
3jx2B-1z9mA:
undetectable		 3jx2A-1z9mA:
17.61
3jx2B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.14A 3jx3A-1z9mA:
undetectable
3jx3B-1z9mA:
undetectable		 3jx3A-1z9mA:
17.61
3jx3B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.08A 3jx3A-1z9mA:
undetectable
3jx3B-1z9mA:
undetectable		 3jx3A-1z9mA:
17.61
3jx3B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.11A 3jx4A-1z9mA:
undetectable
3jx4B-1z9mA:
undetectable		 3jx4A-1z9mA:
17.61
3jx4B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.13A 3jx5A-1z9mA:
undetectable
3jx5B-1z9mA:
undetectable		 3jx5A-1z9mA:
17.61
3jx5B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.08A 3jx5A-1z9mA:
undetectable
3jx5B-1z9mA:
undetectable		 3jx5A-1z9mA:
17.61
3jx5B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.06A 3jx6A-1z9mA:
undetectable
3jx6B-1z9mA:
undetectable		 3jx6A-1z9mA:
17.61
3jx6B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.06A 3jx6A-1z9mA:
undetectable
3jx6B-1z9mA:
undetectable		 3jx6A-1z9mA:
17.61
3jx6B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.06A 3nljA-1z9mA:
undetectable
3nljB-1z9mA:
undetectable		 3nljA-1z9mA:
17.61
3nljB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.05A 3nljA-1z9mA:
undetectable
3nljB-1z9mA:
undetectable		 3nljA-1z9mA:
17.61
3nljB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.09A 3nlpA-1z9mA:
undetectable
3nlpB-1z9mA:
undetectable		 3nlpA-1z9mA:
17.61
3nlpB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.08A 3nlpA-1z9mA:
undetectable
3nlpB-1z9mA:
undetectable		 3nlpA-1z9mA:
17.61
3nlpB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 8 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.09A 3nlqA-1z9mA:
undetectable
3nlqB-1z9mA:
undetectable		 3nlqA-1z9mA:
17.61
3nlqB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.10A 3nlqA-1z9mA:
undetectable
3nlqB-1z9mA:
undetectable		 3nlqA-1z9mA:
17.61
3nlqB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.08A 3nlrA-1z9mA:
undetectable
3nlrB-1z9mA:
undetectable		 3nlrA-1z9mA:
17.61
3nlrB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 8 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.08A 3nlrA-1z9mA:
undetectable
3nlrB-1z9mA:
undetectable		 3nlrA-1z9mA:
17.61
3nlrB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.11A 4cx3A-1z9mA:
undetectable
4cx3B-1z9mA:
undetectable		 4cx3A-1z9mA:
17.61
4cx3B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.09A 4cx3A-1z9mA:
undetectable
4cx3B-1z9mA:
undetectable		 4cx3A-1z9mA:
17.61
4cx3B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.13A 4cx4A-1z9mA:
undetectable
4cx4B-1z9mA:
undetectable		 4cx4A-1z9mA:
17.61
4cx4B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.08A 4cx4A-1z9mA:
undetectable
4cx4B-1z9mA:
undetectable		 4cx4A-1z9mA:
17.61
4cx4B-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.06A 5addA-1z9mA:
undetectable
5addB-1z9mA:
undetectable		 5addA-1z9mA:
17.61
5addB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.04A 5adeA-1z9mA:
undetectable
5adeB-1z9mA:
undetectable		 5adeA-1z9mA:
17.61
5adeB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 VAL A 136
ARG A  92
VAL A  56
GLU A 115
 None
 1.10A 5g0pA-1z9mA:
undetectable
5g0pB-1z9mA:
undetectable		 5g0pA-1z9mA:
17.61
5g0pB-1z9mA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1z9m GAPA225
(Homo
sapiens) 		4 / 7 GLU A 115
VAL A 136
ARG A  92
VAL A  56
 None
 1.09A 5g0pA-1z9mA:
undetectable
5g0pB-1z9mA:
undetectable		 5g0pA-1z9mA:
17.61
5g0pB-1z9mA:
17.61