SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1z9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMA_B_NCAB700_0 (EXOTOXIN A)	1z9v	CONSERVED HYPOTHETICAL PROTEIN MTH0776 (Methanothermobac ter thermautotrophic us)	4 / 6	GLY A 80 ALA A 82 TYR A 79 GLU A 27	None	1.00A	1dmaB-1z9vA: undetectable	1dmaB-1z9vA: 24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D9L_A_ACTA501_0 (CTD-PEPTIDE RNA-BINDING PROTEIN 16)	1z9v	CONSERVED HYPOTHETICAL PROTEIN MTH0776 (Methanothermobac ter thermautotrophic us)	4 / 5	PRO A 58 ILE A 56 TYR A 16 TYR A 79	None	1.31A	3d9lA-1z9vA: undetectable 3d9lY-1z9vA: undetectable	3d9lA-1z9vA: 21.62 3d9lY-1z9vA: 6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGP_A_ERYA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	1z9v	CONSERVED HYPOTHETICAL PROTEIN MTH0776 (Methanothermobac ter thermautotrophic us)	5 / 12	ILE A 72 PRO A 73 VAL A 84 ALA A 29 ALA A 30	None	1.15A	5igpA-1z9vA: undetectable	5igpA-1z9vA: 15.28