SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1za6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_A_MK1A901_3 (POL POLYPROTEIN)	1za6	IGG HEAVY CHAIN (Homo sapiens)	5 / 12	GLY B 108 VAL B 81 ILE B 48 VAL B 18 ILE B 20	None	0.85A	2avvB-1za6B: undetectable	2avvB-1za6B: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Z_B_017B201_1 (HIV-1 PROTEASE)	1za6	IGG HEAVY CHAIN (Homo sapiens)	5 / 12	GLY B 108 VAL B 81 ILE B 48 VAL B 18 ILE B 20	None	0.94A	3d1zA-1za6B: undetectable	3d1zA-1za6B: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYZ_B_CCSB109_0 (CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES)	1za6	IGG HEAVY CHAIN (Homo sapiens)	4 / 8	PHE B 301 HIS B 326 ILE B 274 ALA B 328	None	1.01A	4eyzB-1za6B: undetectable	4eyzB-1za6B: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XYZ_A_ACTA103_0 (POLYUBIQUITIN-C)	1za6	IGG HEAVY CHAIN (Homo sapiens)	4 / 4	LEU B 329 ILE B 274 HIS B 326 VAL B 324	None	1.29A	4xyzA-1za6B: undetectable	4xyzA-1za6B: 11.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AVV_A_MK1A901_3","POL POLYPROTEIN;POL POLYPROTEIN","1za6","IGG HEAVY CHAIN","Homo sapiens",5,"GLY B 108;VAL B  81;ILE B  48;VAL B  18;ILE B  20","None","0.85A","2avvB-1za6B:undetectable","2avvB-1za6B:14.16"],["3D1Z_B_017B201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1za6","IGG HEAVY CHAIN","Homo sapiens",5,"GLY B 108;VAL B  81;ILE B  48;VAL B  18;ILE B  20","None","0.94A","3d1zA-1za6B:undetectable","3d1zA-1za6B:14.16"],["4EYZ_B_CCSB109_0","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","1za6","IGG HEAVY CHAIN","Homo sapiens",4,"PHE B 301;HIS B 326;ILE B 274;ALA B 328","None","1.01A","4eyzB-1za6B:undetectable","4eyzB-1za6B:22.25"],["4XYZ_A_ACTA103_0","POLYUBIQUITIN-C","1za6","IGG HEAVY CHAIN","Homo sapiens",4,"LEU B 329;ILE B 274;HIS B 326;VAL B 324","None","1.29A","4xyzA-1za6B:undetectable","4xyzA-1za6B:11.95"]]