SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1za7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1za7 COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		3 / 3 TRP A  94
ALA A 136
VAL A 134
 None
 0.86A 1bdwA-1za7A:
undetectable
1bdwB-1za7A:
undetectable		 1bdwA-1za7A:
13.70
1bdwB-1za7A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1za7 COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		5 / 12 ILE A 145
ALA A 151
LEU A  74
GLU A 176
PRO A 180
 None
 1.45A 3eigA-1za7A:
undetectable		 3eigA-1za7A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1za7 COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		3 / 3 GLN A 113
THR A 115
THR A 114
 None
 0.71A 4fu9A-1za7A:
undetectable		 4fu9A-1za7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1za7 COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		3 / 3 GLN A 113
THR A 115
THR A 114
 None
 0.70A 4fufA-1za7A:
undetectable		 4fufA-1za7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1za7 COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		4 / 8 LEU A  93
LEU A 173
VAL A 171
ILE A  70
 None
 0.86A 4oj4A-1za7A:
undetectable		 4oj4A-1za7A:
21.55