SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		3 / 3 VAL A 247
VAL A 191
TRP A 245
 None
 0.96A 1bdwA-1zagA:
undetectable
1bdwB-1zagA:
undetectable		 1bdwA-1zagA:
4.38
1bdwB-1zagA:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 11 LEU A  10
LEU A  33
SER A 177
VAL A  57
TRP A  63
 None
 1.36A 2po5B-1zagA:
undetectable		 2po5B-1zagA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		4 / 7 GLY A 102
GLN A  70
PHE A  39
PHE A  38
 None
 0.90A 2qwxA-1zagA:
undetectable
2qwxB-1zagA:
undetectable		 2qwxA-1zagA:
23.81
2qwxB-1zagA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 12 LEU A  10
LEU A  33
SER A 177
VAL A  57
TRP A  63
 None
 1.23A 3aqiB-1zagA:
undetectable		 3aqiB-1zagA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		3 / 3 TYR A  41
LEU A  36
ARG A  40
 None
 0.73A 3sufB-1zagA:
undetectable		 3sufB-1zagA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 12 LEU A  10
LEU A  33
SER A 177
VAL A  57
TRP A  63
 None
 1.20A 3w1wA-1zagA:
undetectable		 3w1wA-1zagA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 9 MET A  60
ILE A 180
ARG A 183
LEU A 181
SER A  48
 None
 1.50A 3w1wB-1zagA:
0.0		 3w1wB-1zagA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_1
(ANTI-TICAGRELOR FAB
72, HEAVY CHAIN
ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 9 ILE A  84
THR A  80
TYR A 124
PRO A 136
ASP A 138
 None
 1.50A 5alcH-1zagA:
0.0		 5alcH-1zagA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		5 / 12 GLU A  86
LEU A  81
ASP A  90
GLY A  93
ALA A  26
 None
 1.23A 5kc4A-1zagA:
undetectable		 5kc4A-1zagA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)
(Homo
sapiens) 		4 / 6 PHE A  38
GLY A  31
GLN A  70
TYR A  14
 None
 1.10A 6ag0C-1zagA:
undetectable		 6ag0C-1zagA:
14.23