SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zak'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CBR_A_A80A201_1 (PROTEIN (CRABP-I))	1zak	ADENYLATE KINASE (Zea mays)	5 / 12	LEU A 170 VAL A 166 VAL A 126 GLY A 12 LEU A 40	None None None None AP5 A 223 (-4.7A)	1.14A	2cbrA-1zakA: undetectable	2cbrA-1zakA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_A_SC2A1290_1 (FICOLIN-2)	1zak	ADENYLATE KINASE (Zea mays)	4 / 5	ASP A 90 SER A 35 GLY A 19 ARG A 158	None None AP5 A 223 (-3.6A) AP5 A 223 (-2.9A)	1.08A	2j2pA-1zakA: undetectable 2j2pB-1zakA: undetectable	2j2pA-1zakA: 21.43 2j2pB-1zakA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GC9_A_SAMA401_1 (DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL)	1zak	ADENYLATE KINASE (Zea mays)	3 / 3	GLU A 120 ASP A 119 ASP A 194	None	0.63A	4gc9A-1zakA: undetectable	4gc9A-1zakA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM9_A_FVXA603_1 (TRANSPORTER)	1zak	ADENYLATE KINASE (Zea mays)	5 / 11	ASP A 38 GLY A 19 SER A 35 GLY A 91 ASP A 160	None AP5 A 223 (-3.6A) None AP5 A 223 (-4.9A) None	1.10A	4mm9A-1zakA: undetectable	4mm9A-1zakA: 17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BPH_B_ACTB404_0 (D-ALANINE--D-ALANINE LIGASE)	1zak	ADENYLATE KINASE (Zea mays)	4 / 7	LYS A 18 ARG A 94 GLY A 37 SER A 35	AP5 A 223 (-2.7A) AP5 A 223 (-2.9A) AP5 A 223 (-3.6A) None	1.03A	5bphB-1zakA: 2.1	5bphB-1zakA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DGX_A_017A101_2 (PROTEASE)	1zak	ADENYLATE KINASE (Zea mays)	3 / 3	GLY A 209 ASP A 205 ILE A 25	None	0.45A	6dgxB-1zakA: undetectable	6dgxB-1zakA: 18.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CBR_A_A80A201_1","PROTEIN (CRABP-I)","1zak","ADENYLATE KINASE","Zea mays",5,"LEU A 170;VAL A 166;VAL A 126;GLY A  12;LEU A  40","None;None;None;None;AP5 A 223 (-4.7A)","1.14A","2cbrA-1zakA:undetectable","2cbrA-1zakA:21.62"],["2J2P_A_SC2A1290_1","FICOLIN-2;FICOLIN-2","1zak","ADENYLATE KINASE","Zea mays",4,"ASP A  90;SER A  35;GLY A  19;ARG A 158","None;None;AP5 A 223 (-3.6A);AP5 A 223 (-2.9A)","1.08A","2j2pA-1zakA:undetectable;2j2pB-1zakA:undetectable","2j2pA-1zakA:21.43;2j2pB-1zakA:21.43"],["4GC9_A_SAMA401_1","DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL","1zak","ADENYLATE KINASE","Zea mays",3,"GLU A 120;ASP A 119;ASP A 194","None","0.63A","4gc9A-1zakA:undetectable","4gc9A-1zakA:23.08"],["4MM9_A_FVXA603_1","TRANSPORTER","1zak","ADENYLATE KINASE","Zea mays",5,"ASP A  38;GLY A  19;SER A  35;GLY A  91;ASP A 160","None;AP5 A 223 (-3.6A);None;AP5 A 223 (-4.9A);None","1.10A","4mm9A-1zakA:undetectable","4mm9A-1zakA:17.95"],["5BPH_B_ACTB404_0","D-ALANINE--D-ALANINE LIGASE","1zak","ADENYLATE KINASE","Zea mays",4,"LYS A  18;ARG A  94;GLY A  37;SER A  35","AP5 A 223 (-2.7A);AP5 A 223 (-2.9A);AP5 A 223 (-3.6A);None","1.03A","5bphB-1zakA:2.1","5bphB-1zakA:21.20"],["6DGX_A_017A101_2","PROTEASE","1zak","ADENYLATE KINASE","Zea mays",3,"GLY A 209;ASP A 205;ILE A  25","None","0.45A","6dgxB-1zakA:undetectable","6dgxB-1zakA:18.81"]]