SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		7 / 12 TYR L  36
GLN L  89
PHE L  98
ASN H  35
VAL H  37
ALA H  93
TRP H 103
 None
 0.68A 1h8sA-1zanL:
22.0		 1h8sA-1zanL:
39.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		7 / 12 TYR L  36
GLN L  89
TYR L  94
ASN H  35
VAL H  37
ALA H  93
TRP H 103
 None
 0.89A 1h8sA-1zanL:
22.0		 1h8sA-1zanL:
39.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 7 LEU H  82
MET H  82
LEU H  80
MET H  48
 None
 1.02A 1linA-1zanH:
undetectable		 1linA-1zanH:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 6 ALA H  88
LEU H  82
LEU H  20
LEU H  67
 None
 0.97A 1mt1D-1zanH:
undetectable
1mt1E-1zanH:
0.0		 1mt1D-1zanH:
17.76
1mt1E-1zanH:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		5 / 12 TYR L  71
ALA L  25
ILE L   2
ALA L  34
LEU H 100
 None
 1.11A 1udtA-1zanL:
undetectable		 1udtA-1zanL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		5 / 10 TYR L  71
ALA L  25
ILE L   2
ALA L  34
LEU H 100
 None
 1.10A 1xp0A-1zanL:
undetectable		 1xp0A-1zanL:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		4 / 7 ALA L  34
TYR L  36
TYR H 100
TYR L  94
 None
 1.18A 2ajvH-1zanL:
14.9
2ajvL-1zanL:
26.1		 2ajvH-1zanL:
30.71
2ajvL-1zanL:
69.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1zan FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		4 / 5 LEU L 180
GLY L 129
PRO L 121
VAL L 133
 None
 0.80A 2aojA-1zanL:
undetectable		 2aojA-1zanL:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1zan FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		4 / 7 LEU L 180
GLY L 129
PRO L 121
VAL L 133
 None
 0.75A 2aojB-1zanL:
undetectable		 2aojB-1zanL:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		5 / 12 TYR L  71
ALA L  25
ILE L   2
ALA L  34
LEU H 100
 None
 1.15A 2h42B-1zanL:
undetectable		 2h42B-1zanL:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 6 LEU H  63
MET H  82
LEU H  80
MET H  48
 None
 1.02A 2kuhA-1zanH:
undetectable		 2kuhA-1zanH:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 6 LEU H  80
MET H  48
LEU H  63
MET H  82
 None
 1.10A 2kuhA-1zanH:
undetectable		 2kuhA-1zanH:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 1zan FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		4 / 5 VAL L 133
VAL L 160
GLY L 159
TRP L 149
 None
 1.13A 2p2fA-1zanL:
undetectable		 2p2fA-1zanL:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1zan FAB AD11 HEAVY CHAIN
FAB AD11 LIGHT CHAIN
(Rattus
norvegicus;
Rattus
norvegicus) 		5 / 12 ILE H 210
GLN L 125
VAL H 169
LEU L 161
THR L 179
 None
 1.37A 3em0B-1zanH:
undetectable		 3em0B-1zanH:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 5 TYR H  90
LEU H  80
LEU H  82
ARG H  66
 None
 1.23A 4em2A-1zanH:
undetectable		 4em2A-1zanH:
18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M93_B_ACTB305_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		4 / 4 SER H  19
THR H  21
PHE H  79
LYS H  81
 None
 0.26A 4m93B-1zanH:
25.1		 4m93B-1zanH:
77.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1zan FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 PRO L  40
ILE L  48
SER L 169
 None
 0.79A 5fsaA-1zanL:
undetectable		 5fsaA-1zanL:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1zan FAB AD11 LIGHT CHAIN
(Rattus
norvegicus) 		3 / 3 LEU L 104
ALA L  84
LEU L  78
 None
 0.55A 5uunB-1zanL:
undetectable		 5uunB-1zanL:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 1zan FAB AD11 HEAVY CHAIN
(Rattus
norvegicus) 		3 / 3 THR H  30
THR H  73
ARG H  71
 None
 1.06A 5wm2A-1zanH:
undetectable		 5wm2A-1zanH:
17.83