SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zaw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 12 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 0.81A 2b60A-1zawA:
undetectable		 2b60A-1zawA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 11 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 0.86A 2b60B-1zawA:
undetectable		 2b60B-1zawA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 12 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 0.93A 2nmyB-1zawA:
undetectable		 2nmyB-1zawA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 12 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 0.88A 2nmzB-1zawA:
undetectable		 2nmzB-1zawA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 9 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 1.02A 3ektB-1zawA:
undetectable		 3ektB-1zawA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 10 ALA A  27
GLY A 116
ILE A  24
ALA A  95
ILE A  99
 None
 0.99A 3ekwA-1zawA:
undetectable		 3ekwA-1zawA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		5 / 12 VAL A   0
VAL A  11
LEU A  64
ILE A  10
THR A  60
 None
 1.33A 3elzA-1zawA:
undetectable		 3elzA-1zawA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1zaw 50S RIBOSOMAL
PROTEIN L10
(Thermotoga
maritima) 		4 / 4 MET A  14
SER A  15
LEU A  61
VAL A  11
 None
 1.46A 3vlnA-1zawA:
0.0		 3vlnA-1zawA:
26.24