SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 1c9sA-1zb7A:
undetectable
1c9sK-1zb7A:
undetectable		 1c9sA-1zb7A:
9.28
1c9sK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.26A 1c9sB-1zb7A:
undetectable
1c9sC-1zb7A:
undetectable		 1c9sB-1zb7A:
9.28
1c9sC-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.21A 1c9sC-1zb7A:
undetectable
1c9sD-1zb7A:
undetectable		 1c9sC-1zb7A:
9.28
1c9sD-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 1c9sD-1zb7A:
undetectable
1c9sE-1zb7A:
undetectable		 1c9sD-1zb7A:
9.28
1c9sE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.20A 1c9sF-1zb7A:
undetectable
1c9sG-1zb7A:
undetectable		 1c9sF-1zb7A:
9.28
1c9sG-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 1c9sG-1zb7A:
undetectable
1c9sH-1zb7A:
undetectable		 1c9sG-1zb7A:
9.28
1c9sH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 1c9sH-1zb7A:
undetectable
1c9sI-1zb7A:
undetectable		 1c9sH-1zb7A:
9.28
1c9sI-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.25A 1c9sJ-1zb7A:
undetectable
1c9sK-1zb7A:
undetectable		 1c9sJ-1zb7A:
9.28
1c9sK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 1gtfA-1zb7A:
undetectable
1gtfK-1zb7A:
undetectable		 1gtfA-1zb7A:
9.28
1gtfK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 1gtfB-1zb7A:
undetectable
1gtfC-1zb7A:
undetectable		 1gtfB-1zb7A:
9.28
1gtfC-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.27A 1gtfC-1zb7A:
undetectable
1gtfD-1zb7A:
undetectable		 1gtfC-1zb7A:
9.28
1gtfD-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 1gtfE-1zb7A:
undetectable
1gtfF-1zb7A:
undetectable		 1gtfE-1zb7A:
9.28
1gtfF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 1gtfG-1zb7A:
undetectable
1gtfH-1zb7A:
undetectable		 1gtfG-1zb7A:
9.28
1gtfH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.27A 1gtfI-1zb7A:
undetectable
1gtfJ-1zb7A:
undetectable		 1gtfI-1zb7A:
9.28
1gtfJ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 1gtfP-1zb7A:
undetectable
1gtfQ-1zb7A:
undetectable		 1gtfP-1zb7A:
9.28
1gtfQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 1gtfT-1zb7A:
undetectable
1gtfU-1zb7A:
undetectable		 1gtfT-1zb7A:
9.28
1gtfU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 1gtfU-1zb7A:
undetectable
1gtfV-1zb7A:
undetectable		 1gtfU-1zb7A:
9.28
1gtfV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.20A 1gtfL-1zb7A:
undetectable
1gtfV-1zb7A:
undetectable		 1gtfL-1zb7A:
9.28
1gtfV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.26A 1gtnG-1zb7A:
undetectable
1gtnH-1zb7A:
undetectable		 1gtnG-1zb7A:
9.28
1gtnH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 1gtnM-1zb7A:
undetectable
1gtnN-1zb7A:
undetectable		 1gtnM-1zb7A:
9.28
1gtnN-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 1gtnN-1zb7A:
undetectable
1gtnO-1zb7A:
undetectable		 1gtnN-1zb7A:
9.28
1gtnO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 8 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 1gtnP-1zb7A:
undetectable
1gtnQ-1zb7A:
undetectable		 1gtnP-1zb7A:
9.28
1gtnQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 ILE A 314
SER A 317
LEU A 119
LEU A 303
LYS A 336
 None
 1.40A 1lbcA-1zb7A:
undetectable
1lbcC-1zb7A:
undetectable		 1lbcA-1zb7A:
21.29
1lbcC-1zb7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 PHE A 195
PRO A 197
ILE A 159
GLY A 162
ILE A  45
 None
 1.18A 1sg9A-1zb7A:
undetectable		 1sg9A-1zb7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 1utdD-1zb7A:
undetectable
1utdE-1zb7A:
undetectable		 1utdD-1zb7A:
9.28
1utdE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.28A 1utdG-1zb7A:
undetectable
1utdH-1zb7A:
undetectable		 1utdG-1zb7A:
9.28
1utdH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.25A 1utdA-1zb7A:
undetectable
1utdK-1zb7A:
undetectable		 1utdA-1zb7A:
9.28
1utdK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 1utdM-1zb7A:
undetectable
1utdN-1zb7A:
undetectable		 1utdM-1zb7A:
9.28
1utdN-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.25A 1utdN-1zb7A:
undetectable
1utdO-1zb7A:
undetectable		 1utdN-1zb7A:
9.28
1utdO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.10A 1utdQ-1zb7A:
undetectable
1utdR-1zb7A:
undetectable		 1utdQ-1zb7A:
9.28
1utdR-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 1utdR-1zb7A:
undetectable
1utdS-1zb7A:
undetectable		 1utdR-1zb7A:
9.28
1utdS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 GLY A 238
GLY A 241
PRO A 182
ASP A 173
ASN A 157
 None
 1.15A 1xdsB-1zb7A:
undetectable		 1xdsB-1zb7A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 ALA A 361
GLU A 357
LEU A 360
LEU A 226
GLY A 396
 None
 1.05A 2jfaB-1zb7A:
undetectable		 2jfaB-1zb7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		3 / 3 LEU A 351
TYR A 240
GLY A 188
 None
 0.57A 2ocuA-1zb7A:
undetectable		 2ocuA-1zb7A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 7 ILE A 288
TYR A 289
PHE A 344
ASP A 345
 None
 1.02A 2qebA-1zb7A:
undetectable		 2qebA-1zb7A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 7 ILE A 288
TYR A 289
PHE A 344
ASP A 345
 None
 1.02A 2qebB-1zb7A:
undetectable		 2qebB-1zb7A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 6 GLN A 297
PHE A 296
PHE A 329
LEU A 303
 None
 1.10A 3ablP-1zb7A:
undetectable
3ablW-1zb7A:
undetectable		 3ablP-1zb7A:
18.67
3ablW-1zb7A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		3 / 3 LYS A 381
ILE A  45
PHE A  37
 None
 1.00A 3j7zS-1zb7A:
undetectable
3j7za-1zb7A:
undetectable		 3j7zS-1zb7A:
13.89
3j7za-1zb7A:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 ILE A  99
MET A  92
PHE A  96
ILE A 193
LEU A 232
 None
 1.34A 3qg2B-1zb7A:
undetectable		 3qg2B-1zb7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		3 / 3 TYR A 289
ASP A 340
ASP A 345
 None
 0.63A 3r24A-1zb7A:
undetectable		 3r24A-1zb7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 7 ILE A 242
LEU A 351
VAL A 330
SER A 338
 None
 0.96A 3r9vA-1zb7A:
undetectable
3r9vB-1zb7A:
undetectable		 3r9vA-1zb7A:
21.57
3r9vB-1zb7A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 ILE A  43
ILE A  99
PHE A 195
ILE A 160
VAL A 235
 None
 1.04A 3tmzA-1zb7A:
undetectable		 3tmzA-1zb7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 ILE A  99
PHE A 195
ILE A 160
ALA A 225
VAL A 235
 None
 1.07A 3tmzA-1zb7A:
undetectable		 3tmzA-1zb7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 LEU A 228
LEU A 360
ILE A 112
LEU A 109
ILE A 193
 None
 1.00A 4odrA-1zb7A:
undetectable
4odrB-1zb7A:
undetectable		 4odrA-1zb7A:
13.41
4odrB-1zb7A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		6 / 11 GLU A 268
GLU A 267
GLY A 274
GLY A 273
ILE A 233
HIS A 230
 FLC  A 501 ( 3.0A)
None
None
None
None
ZN  A 500 ( 3.3A)
 1.38A 4pqaA-1zb7A:
undetectable		 4pqaA-1zb7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 7 LEU A 351
GLY A 241
GLY A 186
ILE A 299
 None
 0.71A 4yjiA-1zb7A:
undetectable		 4yjiA-1zb7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		3 / 3 SER A 174
GLU A 268
GLU A 357
 None
FLC  A 501 ( 3.0A)
None
 0.75A 4ymgB-1zb7A:
undetectable		 4ymgB-1zb7A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 6 GLN A 297
PHE A 296
PHE A 329
LEU A 303
 None
 1.14A 5b1bC-1zb7A:
undetectable
5b1bJ-1zb7A:
undetectable		 5b1bC-1zb7A:
18.67
5b1bJ-1zb7A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 5eeuA-1zb7A:
undetectable
5eeuB-1zb7A:
undetectable		 5eeuA-1zb7A:
9.28
5eeuB-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.20A 5eeuD-1zb7A:
undetectable
5eeuE-1zb7A:
undetectable		 5eeuD-1zb7A:
9.28
5eeuE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 5eeuE-1zb7A:
undetectable
5eeuF-1zb7A:
undetectable		 5eeuE-1zb7A:
9.28
5eeuF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eeuG-1zb7A:
undetectable
5eeuH-1zb7A:
undetectable		 5eeuG-1zb7A:
9.28
5eeuH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.25A 5eeuA-1zb7A:
undetectable
5eeuK-1zb7A:
undetectable		 5eeuA-1zb7A:
9.28
5eeuK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5eeuN-1zb7A:
undetectable
5eeuO-1zb7A:
undetectable		 5eeuN-1zb7A:
9.28
5eeuO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eeuP-1zb7A:
undetectable
5eeuQ-1zb7A:
undetectable		 5eeuP-1zb7A:
9.28
5eeuQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eeuR-1zb7A:
undetectable
5eeuS-1zb7A:
undetectable		 5eeuR-1zb7A:
9.28
5eeuS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eeuS-1zb7A:
undetectable
5eeuT-1zb7A:
undetectable		 5eeuS-1zb7A:
9.28
5eeuT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eeuT-1zb7A:
undetectable
5eeuU-1zb7A:
undetectable		 5eeuT-1zb7A:
9.28
5eeuU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eeuU-1zb7A:
undetectable
5eeuV-1zb7A:
undetectable		 5eeuU-1zb7A:
9.28
5eeuV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.20A 5eevD-1zb7A:
undetectable
5eevE-1zb7A:
undetectable		 5eevD-1zb7A:
9.28
5eevE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5eevE-1zb7A:
undetectable
5eevF-1zb7A:
undetectable		 5eevE-1zb7A:
9.28
5eevF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eevG-1zb7A:
undetectable
5eevH-1zb7A:
undetectable		 5eevG-1zb7A:
9.28
5eevH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.25A 5eevA-1zb7A:
undetectable
5eevK-1zb7A:
undetectable		 5eevA-1zb7A:
9.28
5eevK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eevN-1zb7A:
undetectable
5eevO-1zb7A:
undetectable		 5eevN-1zb7A:
9.28
5eevO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eevP-1zb7A:
undetectable
5eevQ-1zb7A:
undetectable		 5eevP-1zb7A:
9.28
5eevQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5eevR-1zb7A:
undetectable
5eevS-1zb7A:
undetectable		 5eevR-1zb7A:
9.28
5eevS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eevS-1zb7A:
undetectable
5eevT-1zb7A:
undetectable		 5eevS-1zb7A:
9.28
5eevT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eevT-1zb7A:
undetectable
5eevU-1zb7A:
undetectable		 5eevT-1zb7A:
9.28
5eevU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eevU-1zb7A:
undetectable
5eevV-1zb7A:
undetectable		 5eevU-1zb7A:
9.28
5eevV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.20A 5eewD-1zb7A:
undetectable
5eewE-1zb7A:
undetectable		 5eewD-1zb7A:
9.28
5eewE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5eewE-1zb7A:
undetectable
5eewF-1zb7A:
undetectable		 5eewE-1zb7A:
9.28
5eewF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eewG-1zb7A:
undetectable
5eewH-1zb7A:
undetectable		 5eewG-1zb7A:
9.28
5eewH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5eewA-1zb7A:
undetectable
5eewK-1zb7A:
undetectable		 5eewA-1zb7A:
9.28
5eewK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eewN-1zb7A:
undetectable
5eewO-1zb7A:
undetectable		 5eewN-1zb7A:
9.28
5eewO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eewP-1zb7A:
undetectable
5eewQ-1zb7A:
undetectable		 5eewP-1zb7A:
9.28
5eewQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5eewR-1zb7A:
undetectable
5eewS-1zb7A:
undetectable		 5eewR-1zb7A:
9.28
5eewS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eewS-1zb7A:
undetectable
5eewT-1zb7A:
undetectable		 5eewS-1zb7A:
9.28
5eewT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eewT-1zb7A:
undetectable
5eewU-1zb7A:
undetectable		 5eewT-1zb7A:
9.28
5eewU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eewU-1zb7A:
undetectable
5eewV-1zb7A:
undetectable		 5eewU-1zb7A:
9.28
5eewV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5eexD-1zb7A:
undetectable
5eexE-1zb7A:
undetectable		 5eexD-1zb7A:
9.28
5eexE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5eexE-1zb7A:
undetectable
5eexF-1zb7A:
undetectable		 5eexE-1zb7A:
9.28
5eexF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eexG-1zb7A:
undetectable
5eexH-1zb7A:
undetectable		 5eexG-1zb7A:
9.28
5eexH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 5eexI-1zb7A:
undetectable
5eexJ-1zb7A:
undetectable		 5eexI-1zb7A:
9.28
5eexJ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5eexA-1zb7A:
undetectable
5eexK-1zb7A:
undetectable		 5eexA-1zb7A:
9.28
5eexK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eexN-1zb7A:
undetectable
5eexO-1zb7A:
undetectable		 5eexN-1zb7A:
9.28
5eexO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eexP-1zb7A:
undetectable
5eexQ-1zb7A:
undetectable		 5eexP-1zb7A:
9.28
5eexQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5eexQ-1zb7A:
undetectable
5eexR-1zb7A:
undetectable		 5eexQ-1zb7A:
9.28
5eexR-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5eexR-1zb7A:
undetectable
5eexS-1zb7A:
undetectable		 5eexR-1zb7A:
9.28
5eexS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eexS-1zb7A:
undetectable
5eexT-1zb7A:
undetectable		 5eexS-1zb7A:
9.28
5eexT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eexT-1zb7A:
undetectable
5eexU-1zb7A:
undetectable		 5eexT-1zb7A:
9.28
5eexU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eexU-1zb7A:
undetectable
5eexV-1zb7A:
undetectable		 5eexU-1zb7A:
9.28
5eexV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5eeyD-1zb7A:
undetectable
5eeyE-1zb7A:
undetectable		 5eeyD-1zb7A:
9.28
5eeyE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eeyE-1zb7A:
undetectable
5eeyF-1zb7A:
undetectable		 5eeyE-1zb7A:
9.28
5eeyF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eeyG-1zb7A:
undetectable
5eeyH-1zb7A:
undetectable		 5eeyG-1zb7A:
9.28
5eeyH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 5eeyI-1zb7A:
undetectable
5eeyJ-1zb7A:
undetectable		 5eeyI-1zb7A:
9.28
5eeyJ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5eeyA-1zb7A:
undetectable
5eeyK-1zb7A:
undetectable		 5eeyA-1zb7A:
9.28
5eeyK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5eeyN-1zb7A:
undetectable
5eeyO-1zb7A:
undetectable		 5eeyN-1zb7A:
9.28
5eeyO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eeyP-1zb7A:
undetectable
5eeyQ-1zb7A:
undetectable		 5eeyP-1zb7A:
9.28
5eeyQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5eeyQ-1zb7A:
undetectable
5eeyR-1zb7A:
undetectable		 5eeyQ-1zb7A:
9.28
5eeyR-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5eeyR-1zb7A:
undetectable
5eeyS-1zb7A:
undetectable		 5eeyR-1zb7A:
9.28
5eeyS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eeyS-1zb7A:
undetectable
5eeyT-1zb7A:
undetectable		 5eeyS-1zb7A:
9.28
5eeyT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eeyT-1zb7A:
undetectable
5eeyU-1zb7A:
undetectable		 5eeyT-1zb7A:
9.28
5eeyU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eeyU-1zb7A:
undetectable
5eeyV-1zb7A:
undetectable		 5eeyU-1zb7A:
9.28
5eeyV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5eezD-1zb7A:
undetectable
5eezE-1zb7A:
undetectable		 5eezD-1zb7A:
9.28
5eezE-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eezE-1zb7A:
undetectable
5eezF-1zb7A:
undetectable		 5eezE-1zb7A:
9.28
5eezF-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5eezG-1zb7A:
undetectable
5eezH-1zb7A:
undetectable		 5eezG-1zb7A:
9.28
5eezH-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.24A 5eezI-1zb7A:
undetectable
5eezJ-1zb7A:
undetectable		 5eezI-1zb7A:
9.28
5eezJ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5eezA-1zb7A:
undetectable
5eezK-1zb7A:
undetectable		 5eezA-1zb7A:
9.28
5eezK-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eezN-1zb7A:
undetectable
5eezO-1zb7A:
undetectable		 5eezN-1zb7A:
9.28
5eezO-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eezP-1zb7A:
undetectable
5eezQ-1zb7A:
undetectable		 5eezP-1zb7A:
9.28
5eezQ-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5eezQ-1zb7A:
undetectable
5eezR-1zb7A:
undetectable		 5eezQ-1zb7A:
9.28
5eezR-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5eezR-1zb7A:
undetectable
5eezS-1zb7A:
undetectable		 5eezR-1zb7A:
9.28
5eezS-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5eezS-1zb7A:
undetectable
5eezT-1zb7A:
undetectable		 5eezS-1zb7A:
9.28
5eezT-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5eezT-1zb7A:
undetectable
5eezU-1zb7A:
undetectable		 5eezT-1zb7A:
9.28
5eezU-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5eezU-1zb7A:
undetectable
5eezV-1zb7A:
undetectable		 5eezU-1zb7A:
9.28
5eezV-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5ef0D-1zb7A:
undetectable
5ef0E-1zb7A:
undetectable		 5ef0D-1zb7A:
9.28
5ef0E-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5ef0E-1zb7A:
undetectable
5ef0F-1zb7A:
undetectable		 5ef0E-1zb7A:
9.28
5ef0F-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.21A 5ef0G-1zb7A:
undetectable
5ef0H-1zb7A:
undetectable		 5ef0G-1zb7A:
9.28
5ef0H-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5ef0I-1zb7A:
undetectable
5ef0J-1zb7A:
undetectable		 5ef0I-1zb7A:
9.28
5ef0J-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5ef0A-1zb7A:
undetectable
5ef0K-1zb7A:
undetectable		 5ef0A-1zb7A:
9.28
5ef0K-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5ef0N-1zb7A:
undetectable
5ef0O-1zb7A:
undetectable		 5ef0N-1zb7A:
9.28
5ef0O-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef0P-1zb7A:
undetectable
5ef0Q-1zb7A:
undetectable		 5ef0P-1zb7A:
9.28
5ef0Q-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef0Q-1zb7A:
undetectable
5ef0R-1zb7A:
undetectable		 5ef0Q-1zb7A:
9.28
5ef0R-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5ef0R-1zb7A:
undetectable
5ef0S-1zb7A:
undetectable		 5ef0R-1zb7A:
9.28
5ef0S-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef0S-1zb7A:
undetectable
5ef0T-1zb7A:
undetectable		 5ef0S-1zb7A:
9.28
5ef0T-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5ef0T-1zb7A:
undetectable
5ef0U-1zb7A:
undetectable		 5ef0T-1zb7A:
9.28
5ef0U-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5ef0U-1zb7A:
undetectable
5ef0V-1zb7A:
undetectable		 5ef0U-1zb7A:
9.28
5ef0V-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5ef1D-1zb7A:
undetectable
5ef1E-1zb7A:
undetectable		 5ef1D-1zb7A:
9.28
5ef1E-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5ef1E-1zb7A:
undetectable
5ef1F-1zb7A:
undetectable		 5ef1E-1zb7A:
9.28
5ef1F-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.21A 5ef1G-1zb7A:
undetectable
5ef1H-1zb7A:
undetectable		 5ef1G-1zb7A:
9.28
5ef1H-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5ef1I-1zb7A:
undetectable
5ef1J-1zb7A:
undetectable		 5ef1I-1zb7A:
9.28
5ef1J-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.26A 5ef1J-1zb7A:
undetectable
5ef1K-1zb7A:
undetectable		 5ef1J-1zb7A:
9.28
5ef1K-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5ef1A-1zb7A:
undetectable
5ef1K-1zb7A:
undetectable		 5ef1A-1zb7A:
9.28
5ef1K-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5ef1N-1zb7A:
undetectable
5ef1O-1zb7A:
undetectable		 5ef1N-1zb7A:
9.28
5ef1O-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef1P-1zb7A:
undetectable
5ef1Q-1zb7A:
undetectable		 5ef1P-1zb7A:
9.28
5ef1Q-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef1Q-1zb7A:
undetectable
5ef1R-1zb7A:
undetectable		 5ef1Q-1zb7A:
9.28
5ef1R-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5ef1R-1zb7A:
undetectable
5ef1S-1zb7A:
undetectable		 5ef1R-1zb7A:
9.28
5ef1S-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef1S-1zb7A:
undetectable
5ef1T-1zb7A:
undetectable		 5ef1S-1zb7A:
9.28
5ef1T-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.23A 5ef1T-1zb7A:
undetectable
5ef1U-1zb7A:
undetectable		 5ef1T-1zb7A:
9.28
5ef1U-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef1U-1zb7A:
undetectable
5ef1V-1zb7A:
undetectable		 5ef1U-1zb7A:
9.28
5ef1V-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5ef2D-1zb7A:
undetectable
5ef2E-1zb7A:
undetectable		 5ef2D-1zb7A:
9.28
5ef2E-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5ef2E-1zb7A:
undetectable
5ef2F-1zb7A:
undetectable		 5ef2E-1zb7A:
9.28
5ef2F-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.21A 5ef2G-1zb7A:
undetectable
5ef2H-1zb7A:
undetectable		 5ef2G-1zb7A:
9.28
5ef2H-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5ef2I-1zb7A:
undetectable
5ef2J-1zb7A:
undetectable		 5ef2I-1zb7A:
9.28
5ef2J-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5ef2A-1zb7A:
undetectable
5ef2K-1zb7A:
undetectable		 5ef2A-1zb7A:
9.28
5ef2K-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5ef2N-1zb7A:
undetectable
5ef2O-1zb7A:
undetectable		 5ef2N-1zb7A:
9.28
5ef2O-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef2P-1zb7A:
undetectable
5ef2Q-1zb7A:
undetectable		 5ef2P-1zb7A:
9.28
5ef2Q-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef2Q-1zb7A:
undetectable
5ef2R-1zb7A:
undetectable		 5ef2Q-1zb7A:
9.28
5ef2R-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5ef2R-1zb7A:
undetectable
5ef2S-1zb7A:
undetectable		 5ef2R-1zb7A:
9.28
5ef2S-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef2S-1zb7A:
undetectable
5ef2T-1zb7A:
undetectable		 5ef2S-1zb7A:
9.28
5ef2T-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5ef2T-1zb7A:
undetectable
5ef2U-1zb7A:
undetectable		 5ef2T-1zb7A:
9.28
5ef2U-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef2U-1zb7A:
undetectable
5ef2V-1zb7A:
undetectable		 5ef2U-1zb7A:
9.28
5ef2V-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.19A 5ef3D-1zb7A:
undetectable
5ef3E-1zb7A:
undetectable		 5ef3D-1zb7A:
9.28
5ef3E-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.22A 5ef3E-1zb7A:
undetectable
5ef3F-1zb7A:
undetectable		 5ef3E-1zb7A:
9.28
5ef3F-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.21A 5ef3G-1zb7A:
undetectable
5ef3H-1zb7A:
undetectable		 5ef3G-1zb7A:
9.28
5ef3H-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 11 THR A 271
GLY A 238
HIS A 237
THR A 172
ILE A 183
 ZN  A 500 ( 4.4A)
None
None
FLC  A 501 (-4.7A)
None
 1.23A 5ef3I-1zb7A:
undetectable
5ef3J-1zb7A:
undetectable		 5ef3I-1zb7A:
9.28
5ef3J-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.24A 5ef3A-1zb7A:
undetectable
5ef3K-1zb7A:
undetectable		 5ef3A-1zb7A:
9.28
5ef3K-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5ef3N-1zb7A:
undetectable
5ef3O-1zb7A:
undetectable		 5ef3N-1zb7A:
9.28
5ef3O-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.19A 5ef3P-1zb7A:
undetectable
5ef3Q-1zb7A:
undetectable		 5ef3P-1zb7A:
9.28
5ef3Q-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 9 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.20A 5ef3Q-1zb7A:
undetectable
5ef3R-1zb7A:
undetectable		 5ef3Q-1zb7A:
9.28
5ef3R-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.21A 5ef3R-1zb7A:
undetectable
5ef3S-1zb7A:
undetectable		 5ef3R-1zb7A:
9.28
5ef3S-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.17A 5ef3S-1zb7A:
undetectable
5ef3T-1zb7A:
undetectable		 5ef3S-1zb7A:
9.28
5ef3T-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.22A 5ef3T-1zb7A:
undetectable
5ef3U-1zb7A:
undetectable		 5ef3T-1zb7A:
9.28
5ef3U-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 10 GLY A 238
HIS A 237
THR A 172
ILE A 183
THR A 271
 None
None
FLC  A 501 (-4.7A)
None
ZN  A 500 ( 4.4A)
 1.18A 5ef3U-1zb7A:
undetectable
5ef3V-1zb7A:
undetectable		 5ef3U-1zb7A:
9.28
5ef3V-1zb7A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		3 / 3 THR A  81
ASP A  82
ALA A  83
 None
 0.10A 5g5gB-1zb7A:
undetectable		 5g5gB-1zb7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		5 / 12 ILE A 160
ASP A 173
ILE A 138
PHE A  25
MET A  22
 None
 1.37A 5igwA-1zb7A:
0.0		 5igwA-1zb7A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 4 LEU A  95
ASP A 223
PRO A 224
ARG A  98
 None
 1.40A 6fgdA-1zb7A:
undetectable		 6fgdA-1zb7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1zb7 NEUROTOXIN
(Clostridium
botulinum) 		4 / 4 LEU A 385
ASP A 223
PRO A 224
ARG A  98
 None
 0.99A 6fgdA-1zb7A:
undetectable		 6fgdA-1zb7A:
22.01