SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		3 / 3 THR A 175
LEU A 179
VAL A 182
 None
 0.30A 1mz9E-1zbdA:
undetectable		 1mz9E-1zbdA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		4 / 8 TYR A 102
GLU A 163
PHE A 161
VAL A 113
 None
 0.80A 2fl5E-1zbdA:
undetectable
2fl5F-1zbdA:
undetectable		 2fl5E-1zbdA:
20.63
2fl5F-1zbdA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		4 / 4 ILE B  54
ARG A  93
ILE A  57
THR B  47
 None
 1.13A 3ia4C-1zbdB:
undetectable		 3ia4C-1zbdB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		5 / 12 PHE A 110
GLU A 107
GLU A 163
GLU A 140
PHE A 161
 None
 1.46A 4k88A-1zbdA:
3.9		 4k88A-1zbdA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		4 / 8 ILE A  71
LEU A  39
LEU A 179
PHE A  23
 None
 0.97A 4r38B-1zbdA:
undetectable		 4r38B-1zbdA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1zbd RABPHILIN-3A
(Rattus
norvegicus) 		4 / 8 ILE A  71
LEU A  39
LEU A 179
ILE A  99
 None
 0.80A 4r38D-1zbdA:
undetectable		 4r38D-1zbdA:
21.70