SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		3 / 3 ASP 1  75
TYR 1 119
GLU 1 182
 None
 0.78A 1vm1A-1zbe1:
undetectable		 1vm1A-1zbe1:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		4 / 6 ASN 1  91
SER 1 160
ALA 1 121
HIS 1 123
 None
 1.37A 3aruA-1zbe1:
undetectable		 3aruA-1zbe1:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		5 / 10 ALA 1 121
LEU 1 126
LEU 1  53
ALA 1 181
VAL 1  62
 None
 1.12A 3r9cA-1zbe1:
undetectable		 3r9cA-1zbe1:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		4 / 8 ILE 1  42
ILE 1  78
LEU 1  76
ILE 1  51
 None
 0.87A 4dtaB-1zbe1:
undetectable		 4dtaB-1zbe1:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		5 / 12 LEU 1 126
LEU 1  76
MET 1 178
THR 1  56
ILE 1  42
 None
 1.35A 4okbA-1zbe1:
undetectable		 4okbA-1zbe1:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1zbe COAT PROTEIN VP1
(Foot-and-mouth
disease
virus) 		4 / 7 LEU 1 183
ILE 1  42
THR 1  56
MET 1 178
 None
 1.21A 5ljcA-1zbe1:
undetectable		 5ljcA-1zbe1:
18.89