SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 7 TYR A  50
ASN A  42
HIS A 143
GLY A 101
 None
 1.37A 1mxgA-1zbmA:
undetectable		 1mxgA-1zbmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 TYR A  80
PRO A  82
TYR A 149
ILE A 147
VAL A  83
 None
 1.32A 1z9hA-1zbmA:
undetectable		 1z9hA-1zbmA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 TYR A  80
PRO A  82
TYR A 149
ILE A 147
VAL A  83
 None
 1.33A 1z9hB-1zbmA:
undetectable		 1z9hB-1zbmA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 TYR A  80
PRO A  82
TYR A 149
ILE A 147
VAL A  83
 None
 1.33A 1z9hC-1zbmA:
undetectable		 1z9hC-1zbmA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 SER A  56
SER A  75
ASN A  42
THR A  21
ALA A  11
 None
 1.31A 2nniA-1zbmA:
undetectable		 2nniA-1zbmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 6 LEU A  63
ILE A  55
ILE A 199
LEU A 192
 None
 0.89A 2xkwB-1zbmA:
undetectable		 2xkwB-1zbmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 GLY A  73
THR A   8
LEU A  70
SER A  56
ALA A 178
 None
 1.05A 3d91A-1zbmA:
undetectable		 3d91A-1zbmA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 4 GLY A  81
TYR A  80
GLY A  79
ASP A  78
 None
 1.07A 3kl3A-1zbmA:
undetectable		 3kl3A-1zbmA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 191
PHE A  17
ALA A  72
THR A 237
ILE A  38
 None
 1.41A 3ld6A-1zbmA:
undetectable		 3ld6A-1zbmA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 5 TYR A 232
GLN A 146
ILE A 128
PHE A 228
 None
 1.23A 3ls4L-1zbmA:
undetectable		 3ls4L-1zbmA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 248
TYR A 252
THR A 105
GLY A 175
 None
 0.97A 4eq4A-1zbmA:
undetectable		 4eq4A-1zbmA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 175
GLY A  73
VAL A 233
TYR A 232
 None
 0.83A 4fgzA-1zbmA:
undetectable		 4fgzA-1zbmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 175
GLY A  73
VAL A 233
TYR A 232
 None
 0.84A 4fgzB-1zbmA:
undetectable		 4fgzB-1zbmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 248
TYR A 252
THR A 105
GLY A 175
 None
 0.94A 4l39A-1zbmA:
undetectable		 4l39A-1zbmA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 181
ASP A 182
ARG A 180
 None
 0.55A 4wq4B-1zbmA:
undetectable		 4wq4B-1zbmA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 175
TYR A 232
TYR A 236
ILE A  55
ILE A  38
 None
 1.25A 4xucA-1zbmA:
undetectable		 4xucA-1zbmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 175
TYR A 232
TYR A 236
ILE A  55
ILE A  38
 None
 1.26A 4xudA-1zbmA:
undetectable		 4xudA-1zbmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1zbm HYPOTHETICAL PROTEIN
AF1704
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  31
LEU A  29
ILE A   3
SER A  71
 None
 0.71A 5numA-1zbmA:
undetectable		 5numA-1zbmA:
16.00